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ulcerative-colitis Clinical Trials

A listing of ulcerative-colitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 254 clinical trials
M Min Shi

Nicotinamide Riboside in Ulcerative Colitis

This is a randomized, double-blind pilot study of Nicotinamide Riboside (NR) in Pediatric-onset Ulcerative Colitis (UC).

- 18 years of age All Phase N/A
R Reham Elshafiey, PhD

Rupatadine in Patients With Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory condition that primarily targets the large intestine. Although substantial progress has been made in treatment modalities-especially with the development of immunomodulatory drugs and biologic therapies-managing UC continues to present significant challenges. At present, there is no definitive cure, and current treatment strategies are …

18 - 70 years of age All Phase 2

Alpha Lipoic Acid in Ulcerative Colitis

This study aims at evaluating the efficacy and safety of alpha-lipoic acid as adjuvant therapy to mesalamine in patients with mild to moderate ulcerative colitis due to its effect as anti-oxidant and anti-inflammatory drug which can help to improve disease.

18 years of age All Phase N/A
R Reham Elshafiey, PhD

Nitazoxanide in Patients With Ulcerative Colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel Disease (IBD) that primarily affects the rectum and colon. The severity and persistence of mucosal inflammation are associated with morbidity and mortality.

18 - 65 years of age All Phase 2
M Menofia university Hospitals

Desloratadine in Patients With Ulcerative Colitis

The purpose of this study is to investigate safety and therapeutic efficacy of antihistamine (desloratadine) on inflammation and disease activity when administered as adjuvant therapies with the traditional therapy 5-aminosalisylic acid (mesalamine) in patients with mild to moderate ulcerative colitis.

18 - 65 years of age All Phase 2

An Observational Study to Evaluate Effectiveness and Safety of Upadacitinib in Chinese Adult Participants With Moderate to Severely Active Ulcerative Colitis (UC)

Ulcerative colitis (UC) is a chronic, relapsing, and incurable inflammatory disease of the large intestine. The hallmark clinical symptoms include bloody diarrhea associated with rectal urgency and tenesmus.. This study will assess how effective upadacitinib is in treating UC within a Chinese population. Upadacitinib is an approved drug for treating …

18 years of age All Phase N/A
G Gianluca Ianiro, MD

Superdonor FMT in Patients With Ulcerative Colitis

In the last decades fecal microbiota transplantation (FMT) has been established as a highly effective option in the treatment of recurrent Clostridioides difficile infection (rCDI), with a success rate of nearly 90%. For this reason, it is recommended by international guidelines as a treatment option for this indication in clinical …

18 - 75 years of age All Phase 1/2

Beneficial Effect of Silymarin in Ulcerative Colitis

The goal of this clinical trial is to evaluate the possible beneficial effect of silymarin in Ulcerative Colitis adult patients receiving mesalamine. This is trial that will be conducted on 44 adult patients with Ulcerative Colitis. Patients will be enrolled after obtaining an informed consent from them or their guardians. …

18 - 65 years of age All Phase 2
T Tatiana Diacova, PhD, MS, RD

Effects of Pomegranate Juice on Ulcerative Colitis

The purpose of this study is to determine whether consumption of 237 ml of pomegranate juice daily for 8 weeks will: lower inflammation (in the gut as well as generally in the body) and improve your overall quality of life affect the microbes living in the gut (gut microbiota)

18 years of age All Phase N/A
A Anissa Armet, PhD, RD

Personalized Anti-Inflammatory Fibres in Ulcerative Colitis

The goal of this clinical trial is to determine the clinical effects of two different dietary fibre supplements, acacia gum (AG) and microcrystalline cellulose (MCC), in patients with ulcerative colitis. The main question it aims to answer is: Can the fibre supplements reduce gut inflammation (fecal calprotectin)? Researchers will compare …

15 - 60 years of age All Phase N/A

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