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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,447 clinical trials
S SiWei Bao

SSGJ-707 in Advanced Non-Small Cell Lung Cancer

This trial is a Phase III study. All patients are stage IIIB/C (unsuitable for radical therapy) or IV non-small cell lung cancer(NSCLC), Eastern Cooperative Oncology Group (ECOG) performance status 0-1. The purpose of this study is to evaluate the efficacy and safety of SSGJ-707 comparing Pembrolizumab in subjects with advanced …

18 years of age All Phase 3

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer. This is an multicentre, single Arm, Phase 2 Trial study of Cadonilimab with Cisplatin in the treatment of locally advanced cervical cancer. 29 eligible patients will receive …

18 - 75 years of age Female Phase 2
R Rulin Zhuang, MD,PhD

Cancer of Esophagogastric Junction: Optimized Sweet Versus Ivor-Lewis

This study is being done to see whether Optimized Sweet Procedure is superior than the Ivor-Lewis Procedure Esophagectomy with better long-term outcome and acceptable postoperative short-term outcome or not.

18 - 80 years of age All Phase N/A
M Michael C Robertson, MPH, PhD

Promoting Active Living Among People With Metastatic Breast Cancer

Individuals with metastatic breast cancer are living longer but often face persistent fatigue, functional decline, and psychological distress. Physical activity is generally safe for this population and may alleviate symptom burden. Yet, limited interventions are tailored to the unique and needs and preferences of this population. This study aims to …

18 - 99 years of age All Phase N/A
K Kyung Ha Lee, M.D.

Adjuvant mFOLFIRINOX for High-risk Stage III Colon Cancer

A multicenter, open labeled randomized, phase II trial comparing mFOLFIRINOX and mFOLFOX6 as adjuvant treatment for high risk stage III (pT4N1/2 or pTanyN2) colon cancer

20 - 75 years of age All Phase 2/3
F Fabio Corsi, Professor

Organoids From Breast Cancer Patients Treated With Neoadjuvant Therapy

The aim of this study is to establish patient-derived organoid (PDO) and tumor tissue cultures from breast cancer patients, in order to create personalized, accurate, and reliable preclinical models capable of providing information on the diverse biomolecular portraits of breast cancer. These models may also be used to predict the …

18 years of age Female Phase N/A
A Atiye KAŞ ÖZDEMİR, Lecturer, PhD

Sexual Functıon in Young Women After Breast Cancer Surgery

The aim of this observational study was to analyse sexual function in young women after breast cancer surgery. The main question it aims to answer is Sexual function in young women after breast cancer surgery changes during the one-year follow-up period. Participants will answer demographic information, Female Sexual Function Scale, …

18 - 50 years of age Female Phase N/A
E Echo Warner, MPH, PhD, SB

Microvideos for Improving HPV Vaccination Among Childhood Cancer Survivors

This exploratory mixed-methods study aims to examine receipt of treatment and decision-making among rural cancer patients in Utah. Guided by Conceptual Model of Healthcare Access, the study will integrate, survey and cancer registry data with patient interviews to better understand how travel burden, socioeconomic conditions, health literacy, and other contextual …

18 - 26 years of age All Phase N/A
G Giovanni Blandino, Doctor

Study of the Contribution of Mutant p53/YAP Proteins to Therapy Resistance in Recurrent Head and Neck Cancer

Multicenter, non-interventional, retrospective/prospective study of a biological nature, on patients affected by head and neck tumors, for which the collection and use of tissue samples is planned for the study of the mutational profile, the transcriptional profile and the proteomic profile.

18 years of age All Phase N/A
P Panagiotis Balermpas, Prof. Dr.

Comparing Closed Face Masks vs Surface Guided Radiation Therapy for Head and Neck Radiotherapy

At present, open-face masks are used only in patients with claustrophobic anxiety, while all other patients are still immobilized with closed masks, thereby overlooking the need for improvement in patient comfort. Closed face masks in patients undergoing head and neck irradiation have never been compared to no masks in the …

18 years of age All Phase N/A

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