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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 13,633 clinical trials
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Sintilimab and Chemotherapy Sequential Radiotherapy in Advanced Esophageal Cancer

This is an investigator-initiated, single-arm, exploratory clinical study.The study population consisted of treatment naive advanced esophageal squamous cell carcinoma patients. The purpose of this study was to evaluate the efficacy and safety of immunotherapy combined with chemotherapy and residual lesions irradiation of esophageal squamous cell carcinoma.

18 - 80 years of age All Phase 2/3
M Meng Maobin M, MD

Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer

A phase II clinical trial of stereotactic radiosurgery versus radiofrequency ablation in the treatment of inoperable primary liver cancer in specific sites

18 - 75 years of age All Phase 2
K Kaiyan Zhang, M.D.

Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)

To evaluated the safety and efficacy of genomic biomarker-guided neoadjuvant therapy for locally advanced and oligometastatic prostate cancer.

18 years of age Male Phase 2
J Jianhong Peng, Doctor

Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer

In the treatment of locally advanced rectal cancer, the short-term and long-term efficacy of the traditional sandwich regimen has not reached satisfactory efficacy. For this reason, the concept of reducing the dose of postoperative chemotherapy or directly moving forward the full amount of postoperative chemotherapy was proposed, which is called …

18 - 75 years of age All Phase 2

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer. This is an multicentre, single Arm, Phase 2 Trial study of Cadonilimab with Cisplatin in the treatment of locally advanced cervical cancer. 29 eligible patients will receive …

18 - 75 years of age Female Phase 2
L Louqian Zhang, MD

Cancer of Esophagogastric Junction: Optimized Sweet Versus Ivor-Lewis

This study is being done to see whether Optimized Sweet Procedure is superior than the Ivor-Lewis Procedure Esophagectomy with better long-term outcome and acceptable postoperative short-term outcome or not.

18 - 80 years of age All Phase N/A
G Gert De Meerleer, Prof. Dr.

Metastasis-directed Therapy in Oligoprogressive Castration-refractory Prostate Cancer

Evaluation of the impact of metastasis-directed therapy in patients with castration-refractory prostate cancer and a maximum of 5 progressive lesions.

18 years of age Male Phase 3
D Daniela Svetlovska

Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer.

Germ cell tumors (GCTs) are highly curable malignancies; however, a subset of patients with relapsed or refractory disease after first- and second-line chemotherapy have a very poor prognosis, with long-term survival rates below 5%. New therapeutic strategies are needed in this setting. Emerging evidence indicates that extracellular DNA and markers …

18 years of age Male Phase 2
S Silvana Wijaya, MD

Neoadjuvant ADG126 and Pembrolizumab in Locally Advanced Colorectal Cancer

This is a single site, open-label, single-arm phase II study to determine feasibility, tolerability, and preliminary efficacy of neoadjuvant ADG126 and pembrolizumab in stage II or III colorectal cancer.

21 years of age All Phase 2
H Huojun Zhang, M.D.

Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer

The aim of this trial is to compare the safety outcomes of Hypofractionated postprostatectomy radiotherapy (HYPORT) and Conventionally fractionated postprostatectomy radiotherapy(COPORT) in treating patients with localized prostate cancer. Accumulating evidence has proven the safety and feasibility of HYPORT for localized prostate cancer.But for localized prostate cancer,the optimal dose per fraction …

years of age Male Phase N/A

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