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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,299 clinical trials
D Daniel Costa, MD, PhD

Osimertinib In EGFR Mutant Lung Cancer

This research study is studying a targeted therapy as a possible treatment for Non-Small Cell Lung Cancer (NSCLC) with an EGFR mutation. The names of the study drug involved in this study is: Osimertinib (Tagrisso)

18 years of age All Phase 2
S Simon Wernhart, MD

Exercise in Triple- Negative Breast Cancer

This is a prospective, randomized, controlled mono-center study investigating the effects of a combined, supervised aerobic exercise and resistance training in female patients with newly diagnosed, therapy-naive triple-negative breast cancer (TNBC, stage I-III) between 18 and 50 years of age scheduled for anthracycline-based chemotherapy and immunotherapy with checkpoint inhibitors. All …

18 - 65 years of age Female Phase N/A
B Bruno Christian Köhler

Sacituzumab Govitecan in Metastatic Colorectal Cancer

This is a Phase: II/III, open-label, multicenter (at least four centers in Germany) study of Sacituzumab Govitecan (SG) in metastatic colorectal cancer patients who are refractory to at least two lines of standard of care chemotherapy and not eligible for local therapy. There is no upper limit in the previous …

18 years of age All Phase 2/3
C Can LAFÇI, PhD(c)

Prevention of Constipation in Cancer Patients

Constipation is the third most common symptom in patients undergoing chemotherapy, with an incidence rate ranging from 31% to 90%. Despite its high prevalence and adverse effects on patients, constipation is often not reported by patients and is not frequently monitored by nurses, resulting in delays in treatment and care. …

18 years of age All Phase N/A
J Juliana H Earwood, OTD, OTR/L

Cognitive Rehabilitation Following Breast Cancer Treatment

The goal of this proposed project is to evaluate the feasibility and preliminary effect of metacognitive strategy training to improve activity performance, cognition, and quality of life in breast cancer survivors with cancer-related cognitive impairment (CRCI). The other goal of this proposed project is to examine the effects of CO-OP …

20 - 75 years of age Female Phase N/A
S Serena Barbaro, M.Sc.

Pembrolizumab in High-risk Thyroid Cancer

This window of opportunity trial is studying a checkpoint inhibitor agent to treat differentiated thyroid cancer in a neoadjuvant setting. A checkpoint inhibitor is a compound aimed at restoring tumor immunosurveillance. The name of this agent is pembrolizumab.

18 years of age All Phase 2

Blood Screening for Adult Colorectal Cancer

Multicenter, inter-regional, case-control study with the primary objective of evaluating the discriminative power of the blood biomarker TFPI-1 to separate patients with histologically proven CRC from an asymptomatic control population between 50 and 75 years of age with normal colonoscopy.

18 - 75 years of age All Phase N/A
G Giovanni Marchegiani, MD; PhD, Professor

Surgery for Locally Unresectable Pancreatic Cancer

Pancreatic cancer is a severe disease often diagnosed at an advanced stage, when surgery is not possible. New chemotherapy treatments can sometimes shrink the tumor and make surgery an option. This study aims to understand if surgery after such treatments can improve survival and quality of life in selected patients …

18 years of age All Phase N/A
W Wenjin Yin

Trastuzumab Deruxtecan in Advanced Breast Cancer

To evaluate the efficacy and safety of trastuzumab deruxtecan in advanced breast cancer patients.

18 years of age All Phase N/A
K Kyle A Smith, PhD, RD

Researching Economical Adjuvants to Cancer Therapy

The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the investigators if combining beta-glucan with single bouts of exercise provides additional benefit. The main questions it aims to answer are: Does beta-glucan …

18 - 45 years of age All Phase 0

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