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Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,380 clinical trials
K Kathleen Moore, BA

Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors

This study will evaluate the utility of ctDNA detection in patients with high-risk stage I, stage II, and stage III germ cell tumor disease to develop a tool for post-treatment cancer cell detection.

18 years of age All Phase N/A
C Cancer Clinical Trials Team

Tumor Microenvironment Analysis of Prostate Cancer Metastasis

The purpose of this study is to collect prostate cancer tissue from males with metastatic prostate cancers in order to study the tumor microenvironment (TME), which is the area surrounding the tumor including cells, blood vessels, etc., in men with metastatic prostate cancer. The type of research performed on these …

18 years of age Male Phase N/A
X Xiaoguang Shao, Doctor

Maximal Tumor Eradication for Oligometastatic Prostate Cancer

In China, the incidence of prostate cancer is increasing in recent years, and it has ranked 5th among common male tumors and 1st in urinary tumors. Unlike developed countries in Europe and the United States, in China, because prostate-specific antigen (PSA) screening has not been widely popularized, and early prostate …

18 - 75 years of age Male Phase 2/3
A Anthony YB Teoh, FRCSEd(Gen)

EUS-guided RFA for Solid Abdominal Neoplasms

Radiofrequency ablation has been used for treatment of solid neoplasms of the liver, lung, kidney and adrenal. Recently, EUS-guided RFA has become available and the device allows EUS-guided treatment of solid abdominal neoplasms. The procedure has been shown to be feasible in the porcine pancreas and was used to treat …

18 years of age All Phase N/A
D Daan Knapen, MD

CD8 PET Imaging in Metastatic Solid Tumours

This is a multi-center, single-arm trial designed to evaluate the safety and imaging characteristics of 89Zr-Df-crefmirlimab in patients with locally advanced or metastatic solid tumours prior to and during PD-1 antibody therapy.

18 years of age All Phase 2

Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia

The purpose of this study is to evaluate the efficacy and safety of camrelizumab and apatinib as combination therapy in patients with ultra high-risk (Cohort A) and high-risk chemo-refractory or relapsed (Cohort B) gestational trophoblastic neoplasia (GTN). Eligible patients will receive camrelizumab plus apatinib plus chemotherapy. Treatment will be continued …

18 - 60 years of age Female Phase 2
M MD

TT-702 in Patients With Advanced Solid Tumours.

This clinical trial is evaluating the drug candidate TT-702 in patients with advanced solid tumours. The main aims of the trial are to determine the maximum dose of TT-702 that can be given safely to patients alone and in combination with other anti-cancer agents.

16 years of age All Phase 1/2
M Michael Elmkvist Andersen, MD

Circulating Tumor DNA Guided Treatment Monitoring in Advanced Lung Cancer

The study is a prospective randomized interventional study including patients with advanced non-small cell lung cancer, receiving immunotherapy, with the aim of optimizing treatment monitoring. The study aims to investigate the clinical utility of liquid biopsy monitoring in order to reduce the numbers of inefficient treatments and needless toxicity - …

years of age All Phase N/A
W Wen-Lun Wang, Ph.D

RFA to Prevent Metachronous Squamous Neoplasia Recurrence After Complete Endoscopic Submucosal Dissection

Esophageal cancer is a highly lethal disease, and its incidence is still increasing in the world. Recent advances in image-enhanced techniques such as Lugol chromoendoscopy and narrow band imaging, the number of patients with early esophageal squamous cell neoplasias (ESCNs) detected has markedly increased. Endoscopic submucosal dissection (ESD) enables en …

20 - 90 years of age All Phase N/A
J Jing Ding

A Clinical Study of JS105 in Combination With Other Anti-tumor Therapies in Patients With Solid Tumors

This study is an open-label, multicenter, Phase Ib/II clinical study to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of JS105 in combination with other anti-tumor therapies in patients with advanced solid tumors. Patients will be enrolled in two stages: a dose-escalation stage and a dose-expansion stage.

18 - 75 years of age All Phase 1/2

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