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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials
S Shannon M Chan, FRCS

Upfront EUS CGN/CPN vs Conventional Step up Approach for Inoperable Painful Pancreatic Cancer

Patients with unresectable pancreatic cancer are often demoralized by intractable, persistent and incapacitating pain. It must be managed aggressively and strong opioids are recommended as the mainstay of treatment. However, patients develop opioid-related adverse effects. EUS-guided celiac plexus neurolysis (CPN) and celiac ganglion neurolysis (CGN) has been shown to provide …

18 years of age All Phase N/A
F Francesco Castagnini, MD

Observational Study on AI Accuracy in Diagnosing and Treating Failed or Painful Hip Arthroplasty

Primary Goal: This study aims to evaluate the diagnostic and therapeutic accuracy of GPT-4 (an advanced AI language model) compared to three orthopedic surgeons with varying experience levels in cases of failed or painful total hip arthroplasty. Key Research Questions: Diagnostic Accuracy: Does GPT-4 provide correct, partially correct, or incorrect …

18 - 80 years of age All Phase N/A
B Begüm Ünlü, PhD

Physiotherapist-Supervised Online Exercise in Remote White-Collar Workers

This study evaluates the effects of a physiotherapist-guided online exercise program on pain and functional performance in remote white-collar workers. It is designed as a prospective single-arm study to provide preliminary evidence on the clinical effectiveness of the intervention.

18 years of age All Phase N/A
A Aynur Basaran, MD, Prof.

Does Edema Affect the Adjustment of TENS Amplitude

The goal of this pre-post clinical trial is to compare the amplitude settings of three different frequency TENS modes (Conventional TENS, LF TENS, HF TENS) in patients who had undergone total knee arthroplasty, both with the preoperative state and with the contralateral knee. The main question it aims to answer …

40 years of age All Phase N/A
V Vincent Acebo, PhD

Cannabis Effects as a Function of Sex

The purpose of this research is to assess the impact of cannabis on the analgesic and abuse-related effects between men and women

21 - 55 years of age All Phase 1
M Marie Feser

Chronic Pain in Rheumatoid Arthritis

The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. …

18 years of age All Phase N/A
V Vincent Acebo, PhD

THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy

The purpose of this research is to assess the impact of CBD on the effects of THC.

21 - 55 years of age All Phase 1
V Vincent Acebo, PhD

Age-dependent Effects of Smoked and Oral Delta-9-THC

This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.

18 - 65 years of age All Phase 1
N Neus Calpe, PhD, MsN, RN

Adhesive Devices Versus Elastic Devices for Urinary Catheter Securement in Critically Ill Patients Experimental Study

Nowadays there are two types of urinary catheter securement devices, adhesive and elastic bands. The goal of this clinical trial is to determine which type of device-adhesive or elastic-is more effective for securing urinary catheters in critically ill patients. The study also aims to evaluate the prevention of urethral meatus …

18 - 99 years of age All Phase N/A
J Jeffrey I Gold, PhD

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

The goal of this clinical trial is to to utilize Virtual Reality during their interventional radiology procedure to help reduce any pain and anxiety experienced during the procedure in patients above the age of 8 undergoing interventional radiology procedures. The main questions it aims to answer are: To determine if …

8 years of age All Phase N/A

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