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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials

Pectoral Block in Breast Reduction for Pain Control

A reduction mammoplasty is a commonly performed procedure for patients with symptomatic macromastia. The procedure involves removing breast parenchyma for an overall reduction in breast size and to alleviate patient symptoms, such as back/neck pain, rashes in the inframammary fold, and bra strap indentation. It is well documented in the …

18 - 75 years of age Female Phase 4
J Juan Antonio Díaz-Mancha, PhD

Effectiveness of Diaphragm Treatment in Reducing Low Back Pain

Objective: Determine the benefits of including a Stretching technique of the anterior part of the diaphragm in the supine position in the conventional physiotherapy treatment protocol applied to insurance company patients with mechanical low back pain. design: The aim is to carry out an experimental, analytical, prospective, longitudinal, randomized, single-blind …

18 - 50 years of age All Phase N/A

Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain

The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the …

18 - 100 years of age Female Phase N/A
C Clifton Carey

Comparison of Patient-reported Pain After Initial Archwire Placement

Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective. It is possible that one type of wire engenders more patient discomfort. This study will compare the discomfort levels …

12 years of age All Phase N/A

Study of RTMS Analgesic Effect in Chronic Neuropathic Pain,

The purpose of this study is to compare the analgesic effectiveness of three modes of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic neuropathic pain: Classical rTMS stimulation Deeper rTMS stimulation Sham rTMS stimulation

18 - 80 years of age All Phase N/A
M Michael Shalaby, MD

Genicular Nerve Block for Knee Pain in the ED

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

18 years of age All Phase N/A
A Anders H Springborg, MD

Cryoneurolysis for Acute Postoperative Pain Following Total Knee Arthroplasty

Cryoneurolysis is a regional anaesthetic technique that works by freezing peripheral sensory nerves. This technique can potentially provide analgesia after total knee arthroplasty (TKA). However, the technique is expensive and comprehensive. Pain 24 hours after surgery is associated with high amounts of late acute pain. Therefore, the aim of the …

18 years of age All Phase N/A
A Amélie Apinis-Deshaies Research Coordinator

Cannabidiol After Multi-Trauma for Pain and Opioid Therapy

The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex on CBD treatment response. To this end, this research protocol proposes a comprehensive translational approach including …

18 - 70 years of age All Phase 2
H Hesham Rashid, Professor

Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to …

40 - 75 years of age All Phase N/A
M Madiha Ali, MSOMPT

Comparison of Gongs and Kaltenborn Mobilization on Neck Pain

The aim of this randomized controlled trial is to find the effect of Gongs mobilization in comparison with Kaltenborn mobilization on mechanical neck pain , range of motion and proprioception.A randomized control trial that will include total 44 participants. The first group will receive Gongs mobilization along with conventional therapy …

18 - 65 years of age All Phase N/A

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