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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials
G Ganesan Baranidharan

Spinal Cord Stimulation for Chronic Abdominal Pain Patients

Chronic abdominal pain is a common disorder that can have significant impact on the lives of patients. Treatment options include medication which can have limited effectiveness, be associated with side effects and may lead to tolerance and dependency. Spinal cord stimulation (SCS) is a minimally invasive, therapeutic option for managing …

18 - 130 years of age All Phase N/A
P Pavanpreet Kaur, Resident

Pain After Buffered Vs Non Buffered Articaine

Pain after buffered versus non buffered articaine.

18 - 60 years of age All Phase 2
K Karen Van Manen

Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

Multi-center, randomized, blinded, sham-controlled study to determin the safety and efficacy of the NOVABLOC system on post-operative pain in patients undergoing TKA procedures.

21 years of age All Phase N/A
M Mesut YILMAZ, Dr.

Multisensory Methods and Patient Comfort in Thyroid Biopsy

This quasi-experimental study aims to determine the effect of watching an therapeutic video on patients' pain, anxiety, and comfort levels during thyroid biopsy procedures. The study will be conducted in the interventional radiology unit of Muş State Hospital between July 30, 2025, and August 28, 2026. A total of 68 …

18 - 90 years of age All Phase N/A
J Jan Stefaniak, M.D.

Correlation of Pain Intensity Measurements in Healthy Volunteers Exposed to Unpleasant Stimuli

Pain is an unpleasant sensory and emotional phenomenon that can be caused by tissue damage or potentially harmful stimuli. Pain is by definition a subjective phenomenon, and everyone experiences it differently, which creates problems in its assessment and treatment. There are many ways to measure pain, both through patient self-report …

18 - 40 years of age All Phase N/A

Sensory Distribution and Postoperative Analgesia of Ultrasound-Guided Interfascial Plane Blocks in Living Liver Donors

Living liver donor hepatectomy at our institution routinely includes ultrasound-guided interfascial plane blocks as part of postoperative analgesia. Although these blocks have become increasingly used in donor hepatectomy, their cutaneous sensory distributions and block-related dermatomal coverage have not been systematically evaluated, with only anecdotal reports available in the literature. This …

18 - 65 years of age All Phase N/A

A Study of Single and Multiple Doses of HRS-6257 in Healthy Subjects

This is a phase I, randomised, single-blind placebo-controlled, 2-part study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of single and multiple oral doses of HRS-6257 in healthy volunteers.

18 - 55 years of age All Phase 1
F Fang Luo, M.D.

Pre-emptive Scalp Infiltration with Triamcinolone Acetonide Plus Ropivacaine for Post-Craniotomy Pain in Children

At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the other hand, the particularity of craniotomy adds (such as consciousness obstacle, sleepiness, et al) disturbance to the pain assessment …

2 - 12 years of age All Phase 4
A Antoine Roger, MD

Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial

The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain. Researchers will compare this treatment to a placebo, compresses soaked in water. Participants will be invited to use their compresses if …

18 years of age Female Phase 2

Brief Mindfulness Intervention for Patients at a Free Acute Care Clinic

This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The clinical effects of a 4-minute audio-recorded mindfulness intervention for 100 English-speaking patients and 100 Spanish-speaking patients at a free acute care clinic will be investigated relative to a 4-minute audio-recoding about pain psychoeducation.

18 years of age All Phase N/A

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