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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials

The Value of Standardized Respiratory Rate Monitoring Exercises During Rheumatological Injection Procedures

The goal of this clinical trial is to demonstrate the non-inferiority of standardized breathing control exercises on perceived pain during rheumatological injections procedures compared to standard care consisting of the addition of a local anesthetic. The study population will consist of patients scheduled to undergo therapeutic ultrasound-guided joint or periarticular …

18 years of age All Phase N/A

Combined Intravenous Tramadol and Paracetamol Versus Intramuscular Pethidine for Pain Relief During the First Stage of Labor. Compare the Efficacy and Adverse Effects

The goal of this intervention study is to compare the efficacy and adverse effects of pain relief during the first stage of labor using 75 mg IM pethidine versus the combination of IV 100 mg tramadol and 1000 mg paracetamol. The investigator assume that the combination of IV tramadol and …

years of age Female Phase N/A
P Patti Parker

Preoperative Acetazolamide

The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from …

21 - 65 years of age Female Phase 4

Effectiveness of PRP Pharmacopuncture for Chronic Neck Pain in Cervical Myofascial Syndrome of the Upper Trapezius

The goal of this clinical trial is to learn whether pharmacopuncture with Platelet-Rich Plasma (PRP) is effective for treating chronic neck pain in cervical myofascial syndrome related to the upper trapezius muscle. The main questions it aims to answer are: Is pharmacopuncture with Platelet-Rich Plasma (PRP) effective in reducing chronic …

18 - 59 years of age All Phase N/A
A Ajay Premkumar, MD

Opioid-Sparing Joint Replacement

The goal of this clinical trial is to evaluate whether an opioid-sparing postoperative pain regimen can reduce opioid consumption and maintain effective pain control in adults undergoing anterior total hip arthroplasty for osteoarthritis. The main questions it aims to answer are: Does an opioid-limited regimen result in lower postoperative opioid …

18 years of age All Phase 3

Liposomal Bupivacaine Versus Ropivacaine for Preperitoneal Infiltration Analgesia in Upper Abdominal Laparotomy

Upper abdominal open surgery is associated with significant trauma, and postoperative pain management poses considerable challenges. The inflammatory response triggered by peritoneal incision and the transmission of visceral pain via the vagus nerve are key components of "surgical stress" and pain. A potential intervention strategy involves the local administration of …

18 - 75 years of age All Phase N/A
D Daniela PIRES ROTEIA

Impact of Pain From Injectables Antiretroviral Treatments in HIV-1 Patients Based on the Injection Site (Ventrogluteal or Dorsogluteal) and the Use or Non-use of Virtual Reality Headset

This is a multicenter, randomized, open-label study with a cross-over design. The objective of this project is to compare the intensity of pain induced by injectable antiretroviral (ARV) treatment (Cabotegravir® and Rilpivirine®) in patients infected with HIV-1, depending on the injection site and whether or not they are wearing a …

18 years of age All Phase N/A
c chang Gong

External Mastalgia-oil Versus Placebo in Premenopausal Women With Severe Mastalgia

This is a single-center, double-blind, randomized clinical trial to explore the efficacy and safety of external mastalgia-oil versus placebo in premenopausal women with severe mastalgia.

18 - 60 years of age Female Phase 3
E Ece ACAR

Acute Effects of Myofascial Release in Individuals With Text Neck Syndrome

This study aims to investigate the acute effects of myofascial release therapy on neck pain, functional status, and cervical range of motion in individuals diagnosed with Text Neck Syndrome (TNS). Text Neck Syndrome is increasingly prevalent due to excessive use of smartphones and other digital devices, particularly among young adults. …

18 - 40 years of age All Phase N/A
M Marek Szamborski, MD

Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure.

Our study consists of a combination of regional blockade ('local' anesthesia) of the anterior and lateral chest wall in the form of a thin needle prick and the supply of local anesthetic drugs to the area of the relevant chest wall structures to exclude all stimuli, including pain from the …

18 - 90 years of age All Phase N/A

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