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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials
M Mohamed Eltorki, MBChB, MSc

Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain

Appendicitis is a common condition in children 6-17 years of age, and the top reason for emergency surgery in Canada. Children with appendicitis can have very bad pain in their belly. Children often need pain medications given to them through a needle in their arm called an intravenous (IV). The …

6 - 17 years of age All Phase 3
R Roman Natoli, MD PhD

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following bone union. No attempt will be made to affect the experimental outcome in …

18 - 85 years of age All Phase N/A
A Albert Leung, MD

Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

Chronic neuropathic pain (CNP) is disabling. Research on frontline treatments for CNP, shows inconsistent outcomes and dissatisfaction among Veterans. Veterans and clinicians have shown significant interest in cannabis derivatives (THC, CBD) for neuropathic pain control, but there are no well-controlled trials guiding expectations for benefit and adverse outcomes associated with …

21 years of age All Phase 2
A Ashley Kochuyt

Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are: Does PLIA impact post-operative pain after PAO? Does PLIA impact pain medication usage as measured by …

13 - 50 years of age All Phase 2/3
J James H McAuley, PhD

TITAN Trial: Reducing Phantom Limb Pain in People with Amputations

The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain. The main question it aims to answer is: \- In individuals who have undergone amputations and are experiencing phantom limb pain, what is …

18 years of age All Phase N/A
S Site Public Contact

An Internet-based Program to Help Cancer Survivors Manage Pain

To determine whether an Internet-based pain coping skills program plus enhanced usual care, compared to enhanced usual care alone, yields significant improvements in the co-primary outcomes of pain severity (as measured by the Brief Pain Inventory (BPI)) and pain interference (also measured by the BPI) from baseline to the post-intervention …

18 years of age All Phase N/A
H Hatice Ceylan, Specialist

Effect of TMS on Neuropathic Pain for Patients With Sci

The aim of this study is to evaluate the efficacy of rTMS targeting the anterior cingulate cortex, another stimulation site that may be effective in the treatment of neuropathic pain, and to compare it with motor cortex stimulation.

18 - 65 years of age All Phase N/A

Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive hysterectomy under general anesthesia.

18 - 65 years of age Female Phase 2
S Serkan Polat, MD

Percutaneous Electrolysis of the Upper Trapezius in Chronic Neck Pain

In the planned study, we aim to investigate the effectiveness of percutaneous electrolysis treatment applied to myofascial trigger points in the upper trapezius muscle in patients with chronic neck pain. Two different protocols, a low-intensity (0.5 mA × 90 s) and a high-intensity (3 mA × 3 s × 3 …

18 - 70 years of age All Phase N/A
C Ceren Zorluogullari

EFFECTS OF NERVE GLIDING EXERCISES ON ULNAR-SIDED WRIST PAIN

The purpose of this study is to learn if adding specific "nerve gliding" exercises to a standard physical therapy program helps reduce pain and improve hand function in people with ulnar-sided (pinky side) wrist pain. Participants who have had wrist pain for at least 3 months will be randomly assigned …

18 years of age All Phase N/A

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