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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials
K Kamil Darçın

TPVB or SPSIPB in Pain Management After VATS

The goal of this clinical trial is to compare the analgesic efficacy of thoracal paravertebral block (TPVB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing video-assisted thoracoscopic surgery (VATS). The main questions it aims to answer are: How will the total perioperative opioid consumption of the patients …

18 - 80 years of age All Phase N/A
A Assuit Assuit University, Bachelor

Intrapleural Nebulization of Bupivacain to Reduce Postoperative Pain

Thoracic surgery is now common and as other surgeries evolution of minimally invasive techniques is employed. Video-assisted thoracic surgery (VATS) produces little scar but may produce severe pain that may affect the pulmonary function. Many procedure was developed like intercostal nerve block which require injections at multiple levels, Insertion of …

18 - 70 years of age All Phase N/A
W Wonshik Chee

Cancer Pain Management Using a Web-based Intervention

This study is funded by the HEAL Initiative (https://heal.nih.gov/). Based on Preliminary Studies (PSs), the research team developed and pilot-tested an evidence-based Web App-based information and coaching/support program for cancer pain management (CAPA) that was culturally tailored to Asian American breast cancer survivors using multiple unique features. However, CAPA rarely …

18 years of age Female Phase N/A
A Ammani Brown, BA (Hons) MSc

Neurofeedback for Nociplastic Pain in Rheumatoid Arthritis (NECTAR)

Rheumatoid arthritis is an autoimmune condition, causing inflammation and pain. Yet pain may persist even when inflammation has been treated. This residual pain, called nociplastic pain, has symptoms of a chronic pain condition called fibromyalgia. There are few effective therapies to address this residual pain. Published literature shows that fibromyalgia …

18 - 75 years of age All Phase N/A

High-flow Oxygen for Vaso-occlusive Pain Crisis

Sickle cell disease (SCD) is characterized by recurrent vaso-occlusive pain crisis (VOC), which may evolve to acute chest syndrome (ACS), the most common cause of death among adult patients with SCD. Currently, there is no safe and effective treatment to abort VOC or prevent secondary ACS. Management of VOC mostly …

18 years of age All Phase N/A
D Divya Adhia, Ph.D

Brain Network Stimulation for Chronic Low Back Pain.

This study looks at the non-invasive brain stimulation technique in people with chronic low back pain to see: How effective non-invasive brain stimulation is at improving pain intensity in people with chronic low back pain? How safe non-invasive brain stimulation is and what side effects there may be? What study …

18 - 75 years of age All Phase N/A
R Riccardo Mora, MD

Intraoperative Methadone for the Prevention of Postoperative Pain

The pain felt after orthopedic surgery in the absence of adequate locoregional anesthesia is often insufficiently controlled, especially during the first 24 hours postoperatively. Methadone, due to its long half-life, may provide better pain control after orthopedic surgery when associated locoregional anesthesia cannot be performed. It may be impossible to …

18 - 80 years of age All Phase 3
S Samantha Banbury, PhD

The Use of Cannabidiol Suppositories for Sexual Pain

Research aim: To determine how cannabidiol suppositories might reduce sexual pain during intimacy. Outcomes are also hoped to increase sexual functioning, well-being, and quality of life. Research intention: If cannabidiol suppository intervention reduces sexual pain and increases general well-being, then this research would be repeated on a larger scale, targeting …

18 - 100 years of age All Phase N/A
T Thi Lan Phuong Nguyen, MD, MSc

Comparing PIEB and CEI for Labor Pain Relief

The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural Infusion (CEI), both combined with Patient-Controlled Epidural Analgesia (PCEA). The study aims to evaluate which technique provides superior …

18 - 40 years of age Female Phase N/A
A Ashlie Carter, MD

The Impact of Yoga on Endometriosis-Related Pain

The central hypothesis of the investigators is that the practice of yoga will result in an improvement of endometriosis related pain symptoms for women with endometriosis.

18 - 45 years of age All Phase N/A

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