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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
R Roberta Vastano, PhD

Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.

18 - 70 years of age All Phase N/A
S Silvia Lo Vecchio

Investigation of the Effects of Sleep Deprivation on Itch and Pain Sensitivity

In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep deprivation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. To evaluate the inflammatory state induced by sleep fragmentation via the analysis of …

18 - 60 years of age All Phase N/A
N Natalie Hundt, PhD

MOTIVATE to Improve Outcomes for Older Veterans With Musculoskeletal Pain and Depression

The proposed study seeks to evaluate effectiveness, implementation processes, and cost of MOTIVATE among older Veterans with chronic musculoskeletal (MSK) pain and comorbid depressive symptoms.

60 - 99 years of age All Phase N/A

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

The purpose of this study is to compare using FDA-approved bupivacaine (a numbing medicine), along with the usual medications for post-operative pain control to using the usual medications for postoperative pain control alone. The addition of bupivacaine to the surgical wound site with the usual pain medications could better manage …

18 years of age Female Phase 3
S Stanisa Raspopovic, Prof. Dr.

multiSENSory Stimulation to tArgeT Sensory Loss and chronIc Pain in neurOpathic patieNts

Neuropathy is a costly and disabling health issue, which consists of a degeneration of the peripheral nerves. Even though the causes may be different, such as diabetes or amputation, the consequences for neuropathic patients are multiple and extremely debilitating. Among the alarming symptoms it implicates, chronic pain and sensory loss …

18 - 80 years of age All Phase N/A

Pulsed Electromagnetic Field (PEMF) Therapy for Post-operative Pain Following Orthopedic Surgery

The primary objective of this study is to prospectively determine, at 10 days after orthopedic shoulder or knee surgery, if pulsed electromagnetic field (PEMF) therapy is beneficial in reducing patient-reported post-operative pain, as measured by visual analog scale (VAS). The amount of pain medication taken daily and the physical function …

18 years of age All Phase N/A
J Jan Vognstrup

Boosting Open-Label Placebo Effects in Acute Induced Pain in Healthy Adults

This study is to investigate the effect of open-label placebo (OLP) application on acute pain in an experimental model of acute pain (simulating wound pain: this installation will apply monophasic, rectangular electrical pulses of 0.5ms duration with alternating polarity at 2 Hz frequency. The current will be increased to target …

18 - 65 years of age All Phase N/A
D Denise Wilkes, MD-PhD

Understanding the Effects of Transcutaneous Auricular Neurostimulation for Treatment of Chronic Pain

The purpose of the study is to find out how a stimulation device worn on the ear works. This device is thought to stimulate nerves in the area around the ear to change the signals in the brain. The device has been shown to reduce pain and to reduce the …

18 - 65 years of age All Phase N/A
S Silvia Lo Vecchio

Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity

In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. To evaluate the inflammatory state induced by sleep fragmentation via the analysis of …

18 - 60 years of age All Phase N/A

Esketamine as Treatment for Chronic Pain Due to Endometriosis: a RCT Study

The goal of this randomized controlled trial is to investigate the effect of esketamine versus placebo on the NRS score for chronic pelvic pain. Secondary endpoints are to assess pain scores, side-effects, quality of life, depressive symptoms and pain coping.

18 - 50 years of age Female Phase 3

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