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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
S Serdar Kılınç

Comparison of Efficiency of Interferential Current Application Methods in Chronic Neck Pain

The aim of this study is to evaluate the effects of Interferential Current Therapy on pain, disability, and quality of life in patients with chronic neck pain and to compare the effects of applying Interferential Current Therapy with vacuum electrodes versus carbon-silicon pad electrodes.

20 - 50 years of age All Phase N/A
E Emma Ramsay Milford, DEdPsy

Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care

The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level. The study will aim to find out if the treatments are effective and which children the different treatments are effective for.

8 - 14 years of age All Phase N/A
S Severin Vogt, Dr. med.

Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants

N,N-dimethyltryptamine (DMT) is a classical psychedelic with similar effects like LSD or psilocybin. Preliminary evidence from case series and small open-label trials suggests that psychedelics may be promising candidates for the treatment of several pain-related diseases such as chronic pain, migraine, cluster headache or phantom limb pain. However, data from …

25 - 75 years of age All Phase 1
W Weihua Zhao, Phd

The Power of Belief: Expectation-driven and Placebo Modulation of Empathic Pain

This study investigates how belief and expectation influence empathic pain-the pain we feel when observing others in distress. Healthy adult participants will be randomly assigned to one of three groups: no-treatment control, placebo nasal spray, oxytocin-containing nasal spray. Participants in both the placebo and oxytocin conditions will be informed that …

18 - 30 years of age All Phase N/A

Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques

The aim of this clinical trial is : To evaluate effect of different techniques of irrigant activation: LASER activation sonic activation ultrasonic activation passive needle irrigation On Postoperative pain in vital teeth (Randomized controlled trial) Amount of apical extrusion (In vitro study) Participants will describe their preoperative pain and postoperative …

18 - 50 years of age All Phase N/A
S Sara L. Peterson, PhD

Detecting Change in Muscle Parameters, Pain, and Function with NMES for TTA

The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss. Maintaining a healthy, pain-free residual limb is a primary concern for prosthesis users. Amputees commonly experience muscle deficits leading to mobility issues, poor prosthetic fit, and chronic pain. Neuromuscular electrical stimulation …

18 - 100 years of age All Phase N/A
M Maha Nasr, Assistant professor

The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

Pain is a very important factor in Endodontic treatment, Both intra- and Post-operatively. In case of symptomatic Irreversible pulpitis, a build up of inflammatory mediators makes it very difficult for the operator to reach the desired level of anesthesia in order to deliver a pain free treatment as well as …

18 years of age All Phase N/A
F Frauke Musial, Ph.d.

Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain

Chronic pain significantly impacts individuals and society, with about 30% of Norwegian adults affected, making it the leading cause of long-term sick leave and disability benefits. Concerns over addiction to pain medications highlight the need for non-pharmacological treatments, though many such therapies, often complementary or alternative, are not widely available …

21 - 75 years of age All Phase N/A
B Beni-Suef

KT vs IASTM on Upper Trapezius Myofascial Trigger Points To Compare Effect of KT VS IASTM on Pain Intensity, Pain Pressure Threshold, Cervical Range of Motion and Functional Disability Level.

This study would answer the following question: Is there a difference in the effects between IASTM and KT on pain intensity level, pain pressure threshold, cervical range of motion (ROM), functional disability level and satisfaction level in subjects with upper trapezius myofascial trigger points? The aims of this study are: …

19 - 23 years of age All Phase N/A
T Timothy Johnson, MD

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

The purpose of this study is to assess the ability of long-duration low-intensity therapeutic ultrasound (LITUS) to alleviate bone-fracture related pain over a 12-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from bone-fracture pain. Secondary objectives are to assess …

18 - 80 years of age All Phase 1

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