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surgery Clinical Trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,614 clinical trials
O Osama M Rehab, MD

Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery

This prospective randomized controlled study will be conducted to evaluate the analgesic effect of continuous perineural infusion of methylene blue with bupivacaine on acute postoperative pain and to evaluate its preventive role against chronic phantom pain in patients undergoing lower limb amputation surgery

18 years of age All Phase N/A

Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus

The aim of this study is to investigate the continued usage of standard diabetes medications in the post operative period following bariatric surgery to determine whether this approach may improve long term diabetes control. At present, the standard of treatment in patients with type 2 diabetes is that all medication …

18 years of age All Phase N/A
H Haley Goble, MHA

Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery

Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain. Limb Occlusion Pressure, LOP, is based off the patient's systolic blood pressure plus a safety margin and is typically much lower …

18 years of age All Phase N/A
J Jamal Kara, BSc MSc

Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery

The aim of this study is to determine if a standardized evidence-based opioid prescription following elective hand and forearm surgery at Toronto Western Hospital (TWH) will decrease the number of unused opioid pills consumed by patients while still maintaining adequate pain control as compared to usual treatment. Currently, no standardized …

18 years of age All Phase N/A

GPC3 Targeted Fluorescence Image Guided Surgery of Hepatocellular Carcinoma

This study is to evaluate whether intraoperative fluorescence imaging targeting GPC3 can aid improve the surgical accuracy of hepatocellular carcinoma. The main purposes of this study include: ① To raise the detection rate of hepatocellular carcinoma intraoperatively using the novel NIR-II fluorescence molecular imaging and the GPC-3 targeted fluorophore. ② …

18 - 75 years of age All Phase N/A

Alternate Day Fasting After Surgery for Patients Undergoing Chemotherapy

Endometrial cancer is the most common gynecologic cancer and ovarian cancer is the most lethal. The management of both advanced cancers is a combination of chemotherapy and surgery. Standard of care chemotherapeutic treatment for uterine and ovarian cancers is toxic and severely disruptive to the patient's quality of life with …

18 years of age Female Phase N/A

Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial

The goal of this clinical trial is to assess whether the use of intermittent superficial parasternal intercostal plane blocks reduces opioid usage in patients undergoing cardiac surgery with median sternotomy. Participants randomized to the intervention group will receive the blocks with 0.2% ropivacaine administered via catheters placed in the superficial …

18 years of age All Phase N/A
P Pushpsen Joshi

The Effect of Exercise in Patients Awaiting Bariatric Surgery

The aim of this project is to understand the impact of a four week preoperative exercise programme on fitness and metabolic rate and weight before surgery. A multi-site randomised trial sponsored by UCL, recruiting patients awaiting bariatric surgery for obesity at University College London Hospital (UCLH), Whittington Health NHS Trust, …

18 years of age All Phase N/A

NAD+ Augmentation in Cardiac Surgery Associated Myocardial Injury Trial

A Randomized, Double-blind, placebo-controlled Trial to Evaluate the Efficacy of Oral Nam for the Prevention of Acute Kidney Injury in Patients Undergoing On-Pump Cardiac Surgery

18 years of age All Phase 2
J Julien Jouglen

Impact of Mulstidisciplinary Medication Assessment Review in Surgery Departments

The presence of a clinical pharmacist (for their pharmacological expertise) and a general practitioner (for their somatic expertise) in surgery departments would contribute to improve the management of medications in elderly patients.

65 years of age All Phase N/A

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