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surgery Clinical Trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,614 clinical trials
C Cong-zhi Rao, MD

Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery

Statins have been used to low cholesterol to prevent and treat coronary artery diseases. It was also reported that statins could protect endothelial function and cardiac function during coronary artery bypass graft. The investigators recent found simvastatin reduced myocardial injury during noncoronary artery cardiac surgery in single medical center. The …

18 years of age All Phase N/A
J Jordan Goldhammer, MD

Low Dose Vasopressin vs Phenylephrine in Cardiac Surgery

This is a randomized, open label study to investigate vasopressin versus phenylephrine as a first line pressor in cardiac surgery. All patients >18 years of age presenting for coronary artery bypass graft (CABG), valve surgery, or combined CABG and valve surgery will be screened for inclusion. Patients with ejection fraction …

18 years of age All Phase 4
B Bart Jacher

Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery

Opioid overuse is a widespread public health crisis in the United States with increasing rates of addiction and overdose deaths from prescription opioids. Reducing the need for opiate analgesics in the post-operative setting has become a high priority in minimizing long-term opioid use in surgical patients. This study will serve …

18 - 80 years of age All Phase 4
H Hanife Dogan

Complex Decongestive Physiotherapy Applied After Lymphovenous Anastomosis Surgery

Type of this study: Prospective randomized controlled study. The aim of our study is to compare patients with lymphedema who have undergone lymphovenous anastomosis surgery receiving Complex Decongestive Physiotherapy (CDP), patients with lymphedema who have not undergone surgery who receive Complex Decongestive Physiotherapy, in terms of Extremity Volume, Quality of …

18 - 65 years of age Female Phase N/A

Analgesic Efficacy of Maxigesic in Breast Cancer Surgery

The present study aims to find a perioperative analgesic method that provides sufficient analgesia while reducing immune compromise in cancer surgery. This study is to investigate the analgesic effect and safety of Maxigesic inj. (a combination of acetaminophen 1000 mg and ibuprofen 300 mg), which is added to opioid-based IV-PCA …

20 - 70 years of age Female Phase N/A
S Stacee Baker, MEd, BSN, RN

Skin Preparation for Elective Foot and Ankle Surgery

Surgical site infections (SSIs) make about 31% of all nosocomial infections and they are the most common hospital-acquired infection. For foot and ankle elective interventions, SSI rate is reported between 0.4% and 3.6%. This study will investigate the effectiveness of skin cleaning with isopropyl alcohol and scrubbing with chlorhexidine soap …

18 years of age All Phase 4
W Weiming Zhu, PhD

Surgery Versus Biologics for Stricturing CD--a RCT

The management of stricturing Crohn's disease (CD) remains challenging. Although surgical resection may be the final way to solve it, the efficacy of biologics for symptomatic CD associated strictures was acceptable. In clinical practice, the chioce of treatment is particularly difficult. Therefore, a clinical trial of biologics versus surgery is …

18 - 60 years of age All Phase N/A

Bariatric Surgery and Exercise Interventions: Effects on Muscle

The purpose of this project is to assess the effects of bariatric surgery on muscle structure and function as well as investigating the feasibility of undertaking an exercise intervention post-surgery.

18 - 70 years of age All Phase N/A
D David MOSZKOWICZ

Surgery with Botulinum Toxin a for Incisional Hernia

After laparotomy, treating large incisional hernias (width >= 10cm) proves challenging due to the progressive retraction of lateral abdominal muscles and the separation of rectus muscles. This width is a significant risk factor for repair failure and recurrence. High rates of severe postoperative morbidity, up to 50%, are reported, linked …

18 - 79 years of age All Phase 3
S SEVDE NUR AYDIN KUŞSAN, M.D.

Multimodal Analgesia vs. Femoral Block in ACL Surgery

This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament (ACL) reconstruction under general anesthesia. Adult patients aged 18 to 65 will be randomized to receive either multimodal intravenous analgesia …

18 - 65 years of age All Phase N/A

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