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surgery Clinical Trials

A listing of surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,304 clinical trials
V Vladimir Nekhendzy, MD

Transcranial Electrostimulation and Obstructive Sleep Apnea Surgery

Postoperative pain after major surgery for obstructive sleep apnea (OSA), such as palatopharyngoplasty (PPP) and maxillomandibular advancement (MMA) is moderate-to-severe, and may persist for weeks. Control of this pain may be difficult, because OSA patients are very sensitive to traditional opioid pain medications, and their side effects. Poorly controlled pain …

18 - 70 years of age Both Phase N/A
E Emma Starr, BHSc

No Surgery Trial / Two Dose-escalation Strategies

A randomized study of 145 patients. Patients with a clinical T2-3 N0 rectal cancer will be randomized to two arms (arm A: standard chemoradiation (45 Gy in 25 with concomitant 5-FU or Xeloda chemotherapy) and an external beam boost of 9 Gy compared to arm B: standard chemoradiation (45 Gy …

18 - 80 years of age Both Phase 2/3
T Torunn O Apelseth, PhD

Cold Stored Whole Blood in Cardiothoracic Surgery

In vitro platelet function and post-transfusion platelet recovery of platelets stored in whole blood decline during storage. In this pilot randomized clinical trial we aim to investigate the impact of storage time of whole blood on the effect and safety in treatment of immediate blood loss in patients undergoing complex …

18 - 100 years of age Both Phase N/A
J Juha KA Rinne, MD

Day Case Colectomy: Optimizing Short Stay-surgery.

HRV measurement of patients recovering from laparoscopic colorectal resection for any pathology.

18 - 100 years of age Both Phase N/A
N Nicole Sayers

Symbiotic Use in Post-Bariatric Surgery Patients

The purpose of this double blind, randomized control trial would be to test the efficacy of a once daily, multi strain symbiotic on gut health changes in weight loss surgery patients by testing stool samples prior to administration and then three months post administration of the symbiotic to monitor any …

18 - 100 years of age Both Phase N/A
A Alberto Uribe, MD

Sternotomy PIFB Block in Open Heart Surgery

The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia [MMA]), has a favorable effect on our institutional MMA pain regimen. Subjects will go through the …

18 - 100 years of age Both Phase N/A
N Natalie M Newmeyer, MS, RD, LDN

Multi-Component Prehabilitation for Major Elective Surgery

The purpose of this pilot study is to assess the feasibility of delivering a multicomponent prehabilitation and measuring patient-centered outcomes in older adults undergoing major surgery.

65 - 100 years of age Both Phase N/A
R Rachel H Park, MD

Effect of Nitropaste in Chest Masculinizing Surgery

Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature. While its main indication is for angina pectoris, there have been many studies showing improved survival of axial and random pattern flaps. Furthermore, recent …

18 - 100 years of age Female Phase 4
X Xian Li Deborah Khoo

Chest-Up: Obtaining Safe Positioning for Thoracic Surgery

Thoracotomy surgeries, both open and video assisted, are often carried out in the lateral decubitus position to optimize surgical access to the operative side. However, this position is also associated with mechanical injuries of the shoulder joint ligaments and pulling on the structures of the brachial plexus. The neck is …

21 - 100 years of age Both Phase N/A
D Daniel Mansour, MD

Post-operative Urinary Retention (POUR) Following Thoracic Surgery

Inability to urinate a common complication that happens to many patients after a surgery, especially in men over 60 years of age who undergo surgery on their chest. Urinary retention is uncomfortable, increases anxiety, increases hospital length of stay, and leads to more procedures such as putting in a bladder …

50 - 100 years of age Male Phase 1/2

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