Advanced Filters
noise

Metastatic Cancer Clinical Trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,200 clinical trials
T Tohiyuki Ishiba

Metastasis-directed Therapy for Oligometastases of Breast Cancer

OLIGAMI trial is a multi-institutional, two-arm, open-label, randomized controlled phase III trial being conducted with the participation of 50 hospitals belonging to Japan Clinical Oncology Group. After the first registration, all patients will be performed in a 12-week, subtype-specific, systemic therapy consisting of CDK4/6 inhibitors with hormonal therapy for luminal …

18 - 80 years of age All Phase 3
H Hopkins Breast Trials

Study in Patients With Breast Cancer Leptomeningeal Metastasis

Traditional clinical trials in patients with breast cancer leptomeningeal disease (LMD) are challenging as patients often have a rapidly progressive course and prognosis is poor, making meeting standard eligibility difficult. Furthermore, there is limited information about the biology of LMD. The investigators thus propose a study that is as inclusive …

18 years of age All Phase N/A
A Aleuna Lee

Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

The goal of this study is to observe metabolic features associated with human melanoma tumors.

18 years of age All Phase N/A
B Barbara J O'Brien, MD

Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis

The goal of this project is to develop and validate a reproducible scorecard for the neurological assessment of patients with leptomeningeal metastases that can be used in clinical trials including such patients, as well as in clinical practice.

18 years of age All Phase N/A
Q Qin Zhou

LDRT and Chemoimmunotherapy in NPC With Liver Metastasis

This study aims to evaluate the efficacy and toxicity of adding low-dose radiotherapy to chemoimmunotherapy as a first-line treatment for nasopharyngeal carcinoma patients with liver metastasis.

18 - 70 years of age All Phase 2
D David Shultz, MD

Brain Imaging Biomarkers in Patients With Brain Metastasis

A biomarker is a measurable indicator of the severity or presence of some disease state. In this study, brain metastases patients who will be receiving radiation treatment, will undergo CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans prior to and after radiation treatment to measure these biomarkers. This is …

18 years of age All Phase 2
H Hyo-Cheol Kim, MD

Scout Dose of Resin Microspheres

This study looks at a liver cancer treatment called radioembolization and tests a new, possibly more accurate way to check if the treatment is safe for a patient's lungs. Radioembolization is a procedure where tiny beads containing a radioactive substance (yttrium-90) are injected into the arteries that feed a liver …

19 years of age All Phase N/A

Multi-disciplinary Care for Brain Metastases

This is a health services intervention study aimed at understanding the impact of intensive multi-disciplinary care compared with standard care on patient-reported symptom outcomes and prognostic awareness in patients with brain metastases.

18 years of age All Phase N/A
l li-kun Chen, doctor

Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study

This study evaluates the safety and efficacy of Befotertinib combined with Bevacizumab as a first-line treatment for patients with EGFR mutation-positive advanced non-small cell lung cancer (NSCLC) accompanied by brain or leptomeningeal metastases. It is a single-arm, open-label, prospective Phase II clinical trial aiming to explore the potential benefits of …

15 - 75 years of age All Phase 2
M Moritz Herzog, MD

Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data

The goal of this clinical trial is to test the performance of neuronal networks trained on ultrasonic raw Data (=radiofrequency data) for the assessment of liver diseases in patients undergoing a clinical ultrasound examination. The general feasibility is currently evaluated in a retrospective cohort. The main questions the study aims …

18 years of age All Phase N/A

Simplify language using AI