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Metastatic Cancer Clinical Trials

A listing of Metastatic Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,177 clinical trials
H Hyo-Cheol Kim, MD

Streamlining Radioembolization for CCC and Metastatic Liver Cancer

TARE uses radioactive microspheres (20-60 μm), which are trapped in tumors due to abnormal vasculature, while normal liver sinusoids (≤15 μm) prevent their passage. However, some microspheres may drain into hepatic veins and reach the lungs, risking radiation pneumonitis. Pre-procedural evaluation with angiography and nuclear imaging (MAA scan with SPECT/CT) …

19 years of age All Phase N/A
T Toni Ibrahim, MD

Development of Innovative Preclinical Ex Vivo Models for the Study of Sarcomas and Metastases From Solid Tumors

The goal of this observational study is to learn how tumor tissue and blood samples from patients with sarcomas or metastases can be used to create laboratory models that help researchers study cancer behavior and test new treatments. Participants diagnosed with sarcoma or with bone or lung metastases from solid …

- 85 years of age All Phase N/A
A Andrea Sambri, MD

Biomolecular Markers of Bone Metastasis

The goal of this clinical trial is to characterize the biomolecular profile of bone metastases to define the predisposing profiles of bone metastasis, in patients with breast or lung or renal carcinomas or of the gastroenteric or prostate tract with bone metastasis. The main question it aims to answer is: …

18 years of age All Phase N/A

Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors

This study is based on the finding that tumor cells that are grown in the laboratory can be modified in such a way that, when injected to the patient, they will stimulate his/her immune response. This approach will be evaluated in patients with melanoma and colorectal, gastric, ovarian, breast, lung …

18 years of age All Phase 1/2
G Giancarlo Facchini, MD

Arterial Embolization for the Treatment of Bone Metastases: Prospective Observational Study

To date, arterial embolization constitutes one of the most popular methods in minimally invasive treatment of bone metastases, allowing good results in terms of pain reduction, local control of disease and reduction of peri-operative bleeding, with low invasiveness.

18 years of age All Phase N/A
Q Quynh-Nhu Nguyen, MD

A Phase III Randomized Trial Comparing Stereotactic Body Radiation Therapy (SBRT) vs Conventional Palliative Radiation Therapy for Painful Bone Metastases

To compare increasing doses and different treatment schedules of stereotactic body radiation therapy (SBRT) against standard treatment scheduling.

18 years of age All Phase 3
K Kamil Krystkiewicz, PhD

Carbon Fiber Transpedicular Screws in Treatment of Spinal Metastatic Disease

Background: Spinal metastatic disease constitute a serious clinical problem in oncology. Bones are the third most common organ where metastases are located, and the spine is the place where they are most often located. Due to the complexity of the clinical problem, metastatic spine disease remains of interest to many …

18 years of age All Phase N/A
C Costantino Errani, MD, PhD

Fracture Risk Evaluation of Bone Metastases Derived From Carcinoma

From the archives of the Rizzoli institute all patients (approximately 750) treated for bone metastases from 01/01/2010 to 31/12/2022. A review will be made from the medical records, radiological imaging, and histological data of these patients

18 years of age All Phase N/A

BOne Metastases REgistry for Patients Undergoing cryoAbLation With curatIve purpoSe

BOREALIS is a multicentre, prospective, observational cohort study designed to investigate the effectiveness, feasibility, safety and impact on pain and quality of life of curative-intent cryoablation for the treatment of bone metastases in patients with oligometastatic or bone oligo-progressive disease.

18 years of age All Phase N/A
S Shane Lloyd

Simulation-Free, Single-Fraction Palliative Radiation Therapy for Treatment of Bone Metastases

The goal of this study is to provide proof that patients can be treated with simulation-free, single-fraction palliative radiation therapy with a single in-person visit.

18 years of age All Phase N/A

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