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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 375 clinical trials
H Hana M. Rytter, Ph.d Psych.

Screening Instruments for Measuring Visual Symptoms in Victims of Concussion

Visual dysfunction after mild traumatic brain injury (mTBI) is common but often remain undiscovered during longer periods of time. No valid, reliable and easy-to-use screening instrument for uncovering visual dysfunction exists. Furthermore, it is unknown whether optometric measurements currently used in assessing vision problems are consistent with patients' subjective complaints …

18 - 65 years of age All Phase N/A
M Mozhgan Khodadadi, MA

Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary Study

to examine the relationship between repeated concussions and late decline of brain function. In addition, all participants agreeing to participate in the study will be asked to will their brains to The Krembil Neuroscience Centre Concussion Project at the Toronto Western Hospital with the consent and full knowledge of their …

25 - 85 years of age Male Phase N/A
G Gaurav Gupta, MD

ERP Changes Pre and Post Military Changes

This study looks to investigate the cognitive effects associated with intense, military combat training regimens or so-called repetitive sub-concussive forces. Specifically, study participants will undergo cognitive testing in tandem with EEG recordings pre- and post-military training to assess cognition.

18 - 65 years of age All Phase N/A

Paediatric Brain Injury Following Cardiac Interventions

Children born with congenital heart problems face numerous physical, developmental, and social challenges. Complications in pregnancy have potential to impair brain development, leading a smaller brain volume and less mature brain even in babies born at full term. As the brain is less mature, it may be more susceptible to …

- 12 years of age All Phase N/A
K Katie Rice, MPH, CCRP

Systemic Biomarkers of Brain Injury From Hyperammonemia

Ammonia is a waste product of protein and amino acid catabolism and is also a potent neurotoxin. High blood ammonia levels on the brain can manifest as cytotoxic brain edema and vascular compromise leading to intellectual and developmental disabilities. The following aims are proposed: Aim 1 of this study will …

7 - 18 years of age All Phase N/A
S Shraddha Mainali, MD

Automated Robotic TCD in Traumatic Brain Injury

This study's objective is to determine the safety, feasibility and efficacy of prolonged automated robotic TCD monitoring in critically ill patients with severe TBI across multiple clinical sites with varying levels of TCD availability and experience

18 years of age All Phase N/A
S Stefanie Howell, PhD

Traumatic Brain Injury and Stroke Long Term Outcome

Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation continue after discharge from a rehabilitative program.

18 years of age All Phase N/A

The Utility of Thromboelastography in Traumatic Brain Injury

Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography …

18 - 80 years of age All Phase N/A
V Veronique Marchand-Pauvert, PhD

Neuroplasticity After Proprioceptive Rehabiliation

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the …

18 - 70 years of age All Phase N/A
R Roberto Santa Cruz, Dr.

Ventilatory Parameters in Acute Neurological Injury

The goal of this observational study is to test the association between baseline ventilatory parameters (in particular mechanical power (MP), mechanical power normalized to predicted body weight (MP/PBW) and driving pressure (DP) with the baseline neurological status (assessed through the Glasgow coma score) in adults patients under mechanical ventilation with …

16 years of age All Phase N/A

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