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organ-transplant Clinical Trials

A listing of organ-transplant medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 150 clinical trials
J Joost Daemen, MD, PhD

Safety and Efficacy of Ultrasound Renal Denervation in Kidney Transplantation Patients With Uncontrolled Hypertension

This prospective, single-arm, interventional study is designed to assess the short-term and long-term safety and efficacy of bilateral ultrasound renal sympathetic denervation (RDN) of the native kidneys in renal transplant patients with uncontrolled hypertension. Objectives To assess the short-term and long-term changes in ambulatory and office blood pressure (BP) following …

18 years of age All Phase N/A
J Jianbo Wu, Dr.

Remimazolam Infusion in Kidney Transplant Patients: A Multicenter Study

The goal of this clinical trial is to evaluate the pharmacokinetics (PK) and pharmacodynamics (PD) of remimazolam (CNS 70754) in healthy adult participants. The main questions it aims to answer are: What are the key pharmacokinetic parameters of remimazolam, including peak concentration (Cmax), time to peak concentration (Tmax), area under …

18 - 65 years of age All Phase 1

Pericoronary Adipocyte Size Gradient

Evaluation of pericoronary adipocyte gradient (PCAT) in relationship with local atherosclerotic changes in a patient undergoing heart transplantation.

30 - 90 years of age All Phase N/A
D Daphnée Lamarche, PhD

EPI-STORM: Cytokine Storm in Organ Donors

Kidney and liver transplantation are the treatment of choice and are often the last therapeutic option offered to patients with chronic renal and liver failure. More than 70% of kidneys and liver available for transplantation are obtained from donors following neurological death. Unfortunately, compared to living donation, transplant function, graft …

18 - 80 years of age All Phase N/A
N Naciye Vardar-Yağlı, Prof. Dr.

Knowledge of Cardiovascular Risk Factors in Chronic Kidney Disease Patients

The aim of this study is to assess knowledge of cardiovascular risk factors, physical activity levels, health literacy and perceptions of benefits and barriers to exercise in patients with chronic kidney disease and compare them with healthy people.

18 - 65 years of age All Phase N/A
M Maxime PATUREL, Diététicien, FF CDS

Impact of Nutritional Management on the Frailty of Patients Waiting for Liver Transplantation (Via the LFI Tool)

Cirrhosis is a major public health issue responsible for about 15000 deaths each year. Liver transplantation (LT) remains the only curative treatment for decompensated cirrhosis. Decompensated cirrhotic patients awaiting LT are malnourished, sarcopenic and fragile. The evaluation of the nutritional status of these patients is complex because the anthropometric data …

18 years of age All Phase N/A

Multidimensional Frailty Assessment and Post-Transplant Outcomes in Liver Transplant Candidates

This study will evaluate frailty, nutrition, sarcopenia, and psychological health in people waiting for a liver transplant. The purpose is to understand how these factors affect outcomes before and after transplantation. By identifying patients at higher risk early, the study aims to support the development of better care programs in …

18 - 65 years of age All Phase N/A
A Annalisa Boscolo, MD, PhD

Electrical Activity of the Diaphragm and Respiratory Mechanics During NAVA

Protective ventilatory strategy should be applied to reduce ventilator-induced lung injury (VILI) after Lung Transplantation (LTx) or in case of acute respiratory failure requiring invasive mechanical ventilation. Neurally Adjusted Ventilatory Assist (NAVA) is an assisted ventilation mode in which respiratory support is coordinated by the electrical activity of the diaphragm …

18 years of age All Phase N/A
N Nirit Rotem-Lerer

Testing the Feasibility of a Self-Management Support Program for Patient With Chronic Diseases in Israel

This study explores an intervention to support people in Israel who are living with chronic health conditions such as cancer or after kidney transplantation. It focuses on a well-known international program called the Chronic Disease Self-Management Program (CDSMP), which was developed at Stanford University. The program helps individuals build confidence …

21 years of age All Phase N/A
L Limin Rong, prof and M.D

Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial

This Phase I clinical trial is designed to evaluate the safety, tolerability of XS228 ( iPSC-Derived Motor Neuron Progenitor Cells) in patients with Subacute Spinal Cord Injury

18 - 65 years of age All Phase 1

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