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Orthopedic Surgery Clinical Trials

A listing of Orthopedic Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 126 clinical trials
M Melissa Hines, MD

Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients

The goal of DEEPGAIT study is to determine how serious walking problems are for pediatric cancer patients who have had orthopedic surgery, how they change over time, and what can be done to help. Healthy participants without cancer will also be included in this study in order to better understand …

5 - 20 years of age All Phase N/A
P Phillip Worts, Ph.D.

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

This project is a single-site, randomized controlled trial designed to investigate the impact of a 7-minute mindfulness intervention on pain among patients undergoing kyphoplasty or radiofrequency ablation.

18 years of age All Phase N/A
S Sabrina Donzelli, MD

Constructive Variations of Classic Orthopedic Braces for Spinal Deformity During Growth

The construction methods of the same brace vary on an experiential basis according to who builds them, the prescriber, the characteristics of the patients and also the innovations introduced to ensure greater comfort for the patient. The closure of the brace or the way in which the two shells are …

- 16 years of age All Phase N/A
N Na Young Kim

Effectiveness and Safety of Electrically Powered Orthopedic Exercise Device for Gait Disorders

Aging is a global trend, and consequently, the prevalence of age-related diseases is increasing. Gait disorders are common among the elderly and can result not only from various underlying conditions affecting gait but also from the decline in physiological and neurological functions associated with the normal aging process. Gait is …

19 years of age All Phase 4
R Raffaele Vitiello, MD PhD

Paper-based Electrochemical Point-of-care Device in Diagnostic of Orthopedic Infections

Periprosthetic Joint infections (PJI) and spondylodiscitis are considered some of the most costly infectious diseases because require at least one surgery, prolonged hospitalisation, rehabilitation care, prolonged antibiotherapy, and extended absence from work in working-age patients. Ortho-PoC will face this issue with a smart and highly innovative diagnostic tool, starting from …

18 years of age All Phase N/A
A Ami Knox Program Director of Clinical Research, MBA

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD). The …

18 - 65 years of age All Phase 4
E Eva M Pontén, MD PhD

How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.

Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to contractures, bony deformations, difficulty to walk and impaired manual ability. An acquired …

2 - 18 years of age All Phase N/A
M Malin Rydholm, MD

A New Cancer Rehabilitation Process for Chemotherapy-Induced Foot Neuropathy Using Orthopedic Devices

The goal of this clinical study is to evaluate a new process for assessing and alleviating chemotherapy-induced peripheral neuropathy in the feet in patients treated with chemotherapy for early stage breast cancer. It will also compare two orthopedic interventions for symptom relief. The main questions it aims to answer are: …

18 years of age All Phase N/A
R Rachel Aaron

Emotional Awareness and Expression Therapy for People With Persistent Pain Following Orthopedic Trauma

The purpose of this single-arm trial is to determine the feasibility of emotional awareness and expression therapy (EAET) for individuals with persistent pain following orthopedic trauma. As part of this study, participants will be asked to attend weekly EAET treatment sessions and complete assessments (including pre-treatment, post-treatment, and follow-up) consisting …

18 years of age All Phase N/A
İ İrem Keskinsoy Şimşir, Resident (M.D.)

Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia

The goal of this observational study is to determine the correlation between cerebral oxygenation values measured by near-infrared spectroscopy (NIRS) and other routine monitoring parameters in patients placed in the semi-sitting position. The primary questions investigated are : Do NIRS values correlate with heart rate, invasive mean arterial pressure, and …

18 years of age All Phase N/A

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