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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 936 clinical trials
A Alan Peterson, Ph.D.

Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

The goal of this clinical trial is to test an abbreviated, intensive, multi-couple group version of cognitive-behavioral conjoint therapy for PTSD (AIM-CBCT for PTSD) in an active military and veteran population. The main questions it aims to answer are: Does AIM-CBCT for PTSD improve PTSD symptoms? Does AIM-CBCT for PTSD …

18 years of age All Phase N/A
M Michael Borich, PT, PhD

Disrupting Fear-based Memory Consolidation

This project represents a unique collaborative opportunity to pursue the essential proof-of-principle demonstration that non-invasive interference of sensory cortical memory consolidation shortly after an emotional experience can attenuate the cued fear response and potentially reduce the risk of developing post-traumatic stress disorder (PTSD). If successful, the study results would anchor …

18 - 65 years of age All Phase N/A
M Maria Bragesjö, PhD

Efficacy of Internet-delivered Cognitive-behavior Therapy for PTSD

The goal of this clinical trial is to compare therapist-guided internet delivered prolonged exposure to an active control condition( therapist-guided internet delivered cognitive behavioral therapy containing relaxation techniques) for post-traumatic stress disorder. The objective with this study is to investigate efficacy, mechanisms of change and cost effectiveness of therapist-guided internet …

18 years of age All Phase N/A
D David Hill

Multi-session fMRI-Neurofeedback in PTSD

Post-traumatic stress disorder (PTSD) is a debilitating and highly prevalent psychiatric disorder that develops in the aftermath of trauma exposure (APA, 2013). PTSD has been strongly associated with altered activation patterns within several large-scale brain networks and, as such, it has been suggested that normalizing pathological brain activation may be …

18 - 65 years of age All Phase N/A
W Wafa Azgugu, Study Coordinator

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design. Intervention C - Daridorexant will assess the safety and efficacy of daridorexant in participants with PTSD. Please see NCT05422612 for information on the S-21-02 Master Protocol.

18 - 65 years of age All Phase 2
K Kevin Crombie, PhD

The Influence of Aerobic Exercise on Consolidation of Fear Extinction Learning in PTSD

This study aims to test whether aerobic exercise performed after fear extinction learning improves cognitive, physiological, and neural indices of extinction recall in a sample of trauma-exposed men and women with and without posttraumatic stress disorder (PTSD). Participants will complete a clinical intake visit (Day 0), followed by a three-day …

18 - 64 years of age All Phase N/A
S Sevan Minassian

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People

The clinic of psychological trauma in adolescents still requires further development, whereas it is well documented in adults. This clinic is complex, because it must take into account the nature and type of trauma (recent or not, intentional or not, situations of abuse or sexual violence, etc.), the impact on …

12 years of age All Phase N/A
C Courtney Marcelino

The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans

The goal of this clinical trial is to develop a new behavioral treatment for U.S. combat veterans with post-traumatic stress disorder (PTSD), very brief exposure to combat-related stimuli. The main questions it aims to answer are: How does Very Brief Exposure (combat images and control everyday images) and Visible Exposure …

18 - 50 years of age All Phase N/A
M Murray A Raskind, MD

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

Posttraumatic stress disorder (PTSD) is frequently accompanied by difficulty concentrating, poor memory, and inability to keep up with tasks, which negatively impacts a person's ability to function at work and in relationships. Currently available treatments do not fully relieve all symptoms. A published research report showed positive evidence that the …

18 - 65 years of age All Phase 4
L LEAUNE EDOUARD, Dr

People Bereaved by Violent Death : Negative Event Biases and Temporal Perception

A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident). Bereavement following a violent death constitutes a particular clinical situation, at risk of complications. Research on bereavement after a violent death shows higher risks of psychiatric and somatic complications than in …

18 - 65 years of age All Phase N/A

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