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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 926 clinical trials

Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico

The current study will evaluate TF-CBT delivered via tele-health for youth presenting with trauma symptoms via a randomized controlled trial. Goals of the current study are to examine the effectiveness of Tele-TF-CBT delivered by community providers in Puerto Rico in improving youth trauma outcomes. Goals are also to support the …

7 - 18 years of age All Phase N/A
H Harald Bækkelund, PhD, clinical psych.

Early Support After Exposure to Trauma

A significant proportion of people who are exposed to traumatic events suffer from post-traumatic sequelae, such as post-traumatic stress disorder (PTSD). Indicated preventive interventions soon after trauma could be appropriate. Yet, there is limited evidence for the efficacy of such interventions. Moreover, no evidence-based preventive interventions are readily available for …

16 - 99 years of age All Phase N/A
L Leslie A Morland, PsyD

MDMA-assisted Massed Prolonged Exposure for PTSD

The overall objective of this study is to pilot the VASDHS-adapted Emory MDMA-PE Protocol (aE-MDMA-PE) and assess the effect on clinician-rated PTSD symptoms in veterans who receive different doses of MDMA.

18 - 64 years of age All Phase 3

Mechanisms Underlying the Efficacy of Prolonged Exposure

The primary objective of this research is to collect pilot data that demonstrates that proposed neural, psychophysiological and subjective markers measured before, during, and after treatment change over the course of Prolonged Exposure therapy (PE) for posttraumatic stress disorder (PTSD). The aims of the study are to: (1) examine theoretically …

18 - 90 years of age All Phase N/A
L Leslie A Morland, PsyD

Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD

Leveraging veterans' intimate relationships during treatment for posttraumatic stress disorder (PTSD) has the potential to concurrently improve PTSD symptoms and relationship quality. Brief Cognitive-Behavioral Conjoint Therapy (bCBCT) is a manualized treatment designed to simultaneously improve PTSD and relationship functioning for couples in which one partner has PTSD. Although efficacious in …

18 years of age All Phase 2
A Amanda Baker, PhD

Mechanisms Underlying Efficacy of Prolonged Exposure

The primary objective of this research is to collect pilot data that demonstrates that proposed neural, psychophysiological and subjective markers measured before, during, and after treatment change over the course of Prolonged Exposure therapy (PE) for posttraumatic stress disorder (PTSD). The aims of the study are to: (1) examine theoretically …

18 years of age All Phase N/A

Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

The investigators want to test a treatment for posttraumatic stress disorder (PTSD) especially designed for military veterans and service members with mild traumatic brain injuries (TBI) and PTSD. The treatment will include individual psychotherapy sessions to manage PTSD.

18 years of age All Phase N/A
R Rafael Guimarães Santos

Ayahuasca, Esketamine and PTSD

Double-blind, randomized trial comparing a single dose of oral ayahuasca or esketamine in patients with posttraumatic stress disorder.

18 - 65 years of age All Phase 2
J Jesse R Cougle, Ph.D.

Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms

This study is exploring the efficacy of a digital therapeutic app in reducing symptoms of posttraumatic stress disorder (PTSD) in adults.

18 years of age All Phase 2
I Isabelle McLeod Daphnis, BS

Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers

Healthcare workers and COVID-19 patients may experience psychological distress consequent to the pandemic, and are at particularly elevated risk for experiencing posttraumatic stress disorder (PTSD), based on evidence from previous infectious disease outbreaks. The best-validated treatment for PTSD is exposure therapy. Exposure therapy help patients suffering from PTSD to revisit …

18 years of age All Phase N/A

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