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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 926 clinical trials
D David E Dostal, PhD MA BS

rTMS-augmented Written Exposure Therapy for PTSD

Post-traumatic stress disorder (PTSD) is prevalent and represents a high healthcare burden among Veterans. Repetitive transcranial magnetic stimulation (rTMS) is a brain-based therapy that may be effective for treating PTSD. The theorized mechanism of rTMS is enhancement of emotional flexibility via the dorsolateral prefrontal cortex node of the brain's cognitive …

18 - 50 years of age All Phase N/A

Feasibility of an Intervention for Somatic Flashbacks in PTSD

This trial will explore the feasibility and acceptability of an intervention for Somatic flashbacks in Post-Traumatic Stress Disorder (PTSD). Imagery Rescripting (ImRs) will form a central part of the intervention. The primary objective of this trial is to explore the acceptability and feasibility of delivering an intervention for the management …

16 years of age All Phase N/A
T Tsipi Milman, MD

Efficacy of Reboxetine and Methylphenidate Treatment on Attentional, Sensory and Emotional Dysregulation in Adults With PTSD

Up-to-date, no studies have examined the attentional, sensory and emotional processing (difficulties) among patients diagnosed with Posttraumatic Stress Disorder (PTSD). In addition, the efficiency of drug treatments that focus on the noradrenergic and dopaminergic, and thus influence attention processing and PTSD symptoms through these pathways, have only briefly been investigated. …

20 - 60 years of age All Phase 2
J Joseph Carpenter, PhD MA

Cognitive Processing Therapy (CPT) Memory Support (MS) Study

The efficacy of psychological interventions for posttraumatic stress disorder (PTSD) is likely limited by the difficulty participants have learning and remembering important therapy content. Accordingly, the present study will examine the utility of integrating a Memory Support (MS) intervention into Cognitive Processing Therapy (CPT), an empirically supported and widely disseminated …

18 years of age All Phase N/A
M Mohammed Milad, PhD

Fear and Avoidance in PTSD Patients

The purpose of this research study is to study how the brain learns to avoid certain stimuli or situations using an experimental paradigm. The big goal is to measure brain responses and subject's feelings and expectations when they are learning to actively avoid experimental stimuli, and how fear extinction learning …

18 - 70 years of age All Phase N/A
W Wen Li, PhD

A Neurosensory Account

The goal of this study is to develop and test a novel pathophysiology of PTSD by integrating sensory cortical (SC) and amygdala-PFC dysfunctions into a tripartite Sensory-Prefrontal-Cortex-Amygdala (SPA) model.

18 - 50 years of age All Phase N/A
S Sharon Dekel, Ph.D., M.Phil., M.S.

Preventing Childbirth-Related PTSD With Expressive Writing

The goal of this clinical trial is to test a brief psychological intervention given to individuals in the first days following childbirth who have experienced a potentially stressful childbirth. The treatment is aimed at preventing post-traumatic stress disorder following childbirth and promoting maternal-infant bonding. In the days following childbirth, participants …

18 - 50 years of age Female Phase N/A
S Sigrid Salomonsson, PhD

Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy

A Randomized Controlled Non-inferiority Trial testing if the new experimental Blended Trauma focused cognitive behavioral therapy (B-TF-CBT) for post traumatic stress disorder (PTSD), is non-inferior to gold standard control treatment Prolonged Exposure (PE). Research question and hypothesis Can the blended treatment yield outcomes non-inferior to face-to-face TF-CBT for patients with …

18 years of age All Phase N/A
H Homestead Associates Research Contact

Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant

This is a Phase 2 randomized, double-blinded, placebo-controlled study that will evaluate multiple potential pharmacotherapeutic interventions for PTSD utilizing an adaptive platform trial design. Intervention C - Daridorexant will assess the safety and efficacy of daridorexant in participants with PTSD. Please see NCT05422612 for information on the S-21-02 Master Protocol.

18 - 65 years of age All Phase 2
A Alan Peterson, Ph.D.

RCT of Intensive Multi-Couple Therapy for PTSD Versus Relationship Education in Military Couples

The goal of this clinical trial is to test an abbreviated, intensive, multi-couple group version of cognitive-behavioral conjoint therapy for PTSD (AIM-CBCT for PTSD) in an active military and veteran population. The main questions it aims to answer are: Does AIM-CBCT for PTSD improve PTSD symptoms? Does AIM-CBCT for PTSD …

18 years of age All Phase N/A

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