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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 936 clinical trials
R Robin Hurley, MD

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances. Poor sleep, one of the most common complaints in Veterans with PTSD, can be distressing, impair concentration and memory, and contribute to physical health conditions, such as metabolic syndrome, inflammation, and …

18 - 75 years of age All Phase 4
D Dulce María Rascón Martínez, MSc

Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.

The goal of this randomized clinical trial is to find out whether giving an intravenous lidocaine + dexmedetomidine combination (LIDEX) during laparoscopic bariatric surgery can lower post-operative pain, inflammation, and oxidative stress in adults with obesity. The main questions it aims to answer are: Pain control: Does LIDEX reduce pain …

18 - 60 years of age All Phase 4
A Aysel GÜL, PhD

The Effect of Hand Holding and Stress Ball Intervention on Pain and Anxiety

Cataract surgery is currently primarily performed with topical anesthesia. Although topical anesthesia provides many benefits for patients, they may experience pain, anxiety and discomfort during surgery. It has been reported that increased pain and anxiety during surgery may decrease patient cooperation and satisfaction, making surgery more difficult. In this context, …

18 years of age All Phase N/A

Yoga With and Without VR for Core, Balance, and Stress in University Students

The present study aims to investigate the combined and comparative effects of yoga exercise performed with and without virtual reality (VR) support on stress levels, core stabilization, and balance in university students aged 18-30. Participants will be screened using validated stress assessment tools to ensure inclusion of individuals with moderate …

18 - 30 years of age All Phase N/A
E Eman A Ali, Master

Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy

The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive surgery (laparoscopic cholecystectomy).

20 - 60 years of age All Phase N/A
A Ayse Kardelen ACAR, MSc

Dynamic Neuromuscular Stabilization vs Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence

This randomized controlled trial aims to compare the pre- and post-treatment effects of Dynamic Neuromuscular Stabilization (DNS) training and Pelvic Floor Muscle Training (PFMT) on pelvic floor muscle function, pelvic floor morphometry, urinary symptoms, quality of life, sexual function, and physical activity levels in women with stress urinary incontinence (SUI). …

18 - 65 years of age Female Phase N/A
M Max Davis

Does the Development of the Repeated Bout Effect Depend on Oxidative Stress and Inflammation?

Eccentric exercise, particularly when novel and strenuous, can cause soreness and inflammation, impairing subsequent exercise performance. These performance decrements are attributable to oxidative stress and inflammation. Interestingly, a single bout of eccentric exercise can confer protective effects, ameliorating the negative consequences in subsequent bouts. This is termed the repeated bout …

18 - 45 years of age All Phase N/A

Effect of Mindfulness-Based Stress Reduction on Birth Memory and Perception of Traumatic Birth

This randomized controlled trial aims to evaluate the effects of a Mindfulness-Based Stress Reduction (MBSR) program on birth memory and perception of traumatic birth among women who have undergone vaginal delivery. The study will be conducted between July and October 2025 at Malatya Training and Research Hospital. Participants in the …

18 - 45 years of age Female Phase N/A

REVERSE: Improving Treatment-resistant Post Traumatic Stress Disorder (PTSD) with Glucocorticoid Receptor (GR) Antagonism

Rationale Post-traumatic stress disorder (PTSD) is a psychiatric disorder that can develop in people who have experienced or witnessed a traumatic event. Symptoms of PTSD include flashbacks, nightmares, difficulty sleeping, difficulty concentrating, irritability, and avoidance of people, places, or activities that remind the person of the traumatic event. Even though …

18 years of age All Phase 2
M Michael Treadway, PhD

Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine

The main purpose of this study is to investigate the effects of ketamine on decision-making and emotion processing in a sample of individuals diagnosed with Major Depressive Disorder (MDD).

18 - 65 years of age All Phase 0

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