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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 936 clinical trials

HO-1/CREB3 Modulates Golgi Stress in Patients With Sepsis

This study was an ambispective observational cohort study that included sepsis patients hospitalized in the Intensive care unit (ICU) of the Nankai Hospital. All patients met the consensus criteria of sepsis-3. The purpose of this study is to investigate the valuable biomarkers for the severity of sepsis and predictors of …

18 - 100 years of age All Phase N/A

Behavioral Intervention to Reduce Stress Among Black Gender Minority Women

The research objectives of this study are to first, develop a culturally informed community-based intervention with guidance from community members (via focus groups and theater testing) to reduce the effect of chronic stigma exposure on psychological distress symptoms (PTS and depressive symptoms) among transgender women. Second, the research team will …

18 - 99 years of age Female Phase N/A
C Chloe Ford, MSc

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

The purpose of this study is to assess the safety and effectiveness of co-administered MDMA and psilocybin in military Veterans with a diagnosis of Posttraumatic Stress Disorder (PTSD). To apply or learn more, please view our website: https://hopkinspsychedelic.org/pamvet

21 years of age All Phase 1
J Jeremy A Bigalke, PhD

Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress

This study aims to evaluate the influence of acute oral melatonin supplementation on cardiovascular and skin temperature responses to mental stress. The hypothesis is that acute melatonin will lead to reduced cardiovascular and skin temperature responsiveness to acute mental stress.

18 - 70 years of age All Phase N/A
J Jenni Wise, PhD, MSN

Adapting a Stress Management Intervention to Reduce Cardiovascular Disease Risk

Women living with HIV have 2-4x higher risk for cardiovascular disease compared to women without HIV, with women living with HIV in the Southern US being particularly at risk. While an increased prevalence of traditional risk factors (e.g., hypertension, diabetes, and obesity) partially explain this risk, evidence suggests that increased …

18 years of age Female Phase N/A
M Marc Grasso

Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat

The overall objective of this study it to use Positron Emission Tomography (PET) brain imaging and a radiotracer that measures the epigenetic marker Histone Deacetylase 6 (HDAC6) to examine HDAC6 expression in people with Post-Traumatic Stress Disorder (PTSD), Alcohol Use Disorder (AUD), or concurrent PTSD and AUD with control groups. …

18 - 70 years of age All Phase N/A

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score \> 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately …

18 - 46 years of age Female Phase N/A
B Bengi Gülgü

Effect of Different Root Canal Sealers on Oxidative Stress Markers

The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session. The main questions it aims to answer are: Is there a change in oxidative stress markers measured from …

18 - 45 years of age All Phase N/A
K Keely A Muscatell, PhD

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

The purpose of this study is to map the neural and molecular mechanisms underlying psychological stress-induced changes in inflammation which could reveal new targets for intervention to reduce the risk of cardiovascular disease.

18 - 30 years of age All Phase 4
M Maya Waintraub, M.S.

Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults

This randomized, double-blind, placebo-controlled clinical trial evaluates whether 70 days of daily cranberry juice consumption improves cognitive performance and motor accuracy and reduces psychological and physiological stress responses during a motor-cognitive dual-task multitasking challenge in healthy adults aged 30-55 (Aim 1). It is hypothesized that chronic cranberry juice intake will …

30 - 55 years of age All Phase N/A

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