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Stress Clinical Trials

A listing of Stress medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 909 clinical trials
D David G Edwards, PhD

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

High sodium diets impair vascular function, which may influence the work of the heart. This investigation is designed to determine if this change in vascular function results in a greater workload in the heart and if people who regularly exercise are protected from these effects.

21 - 45 years of age All Phase N/A
J Junhyung Kim, MD, PhD

Alleviating Stress by Mobile Application' for Depression

This study is a single-blind, multicenter, randomized, controlled crossover trial. The App, developed in South Korea, is an application that provides integrated interventions for stress reduction for the general population. The App provides three contents based on MBSR, CBT, and relaxation sounds that are known to be effective in stress …

19 - 65 years of age All Phase N/A
C Cory K Chen, Ph.D.

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

This is a randomized controlled trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) in comparison with TAU (at the VA) in a 2:1 ratio in 75 Veterans with PTSD who have not responded to standard treatment at the VA.

18 - 70 years of age All Phase N/A
B Bella Ruiz, BS

Targeting Endoplasmic Reticulum Stress in Human Hypertension

There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill this gap by performing a single-blind, placebo-controlled trial in humans with hypertension.

18 - 80 years of age All Phase 1/2

Sympathetic Overactivity in Post-traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily …

18 - 65 years of age All Phase N/A

JOB STRESS in OPHthalmology Physicians and Residents

Ophthalmology physicians and residents work under stress conditions during night emergency ophthalmology shifts. Under time pressure, that is a characteristic of the urgency of care, they must use all their cognitive resources to make an accurate diagnosis and to provide accurate decisions, with sometimes surgical emergency acts. In addition, in …

18 - 65 years of age All Phase N/A
T Tami Bar-Shalita, PHD

Sensory Modulation Dysfunction and Posttraumatic Stress Disorder

To explore the role of sensory modulation dysfunction (SMD) (i.e., a neurodevelopmental state altering the sensory perception, severely interfering with daily function) as a risk factor for posttraumatic stress disorder (PTSD), its co-occurring pain, and impeded cognitive functions, following exposure to combat trauma.

18 - 28 years of age All Phase N/A

Mental Stress Reactivity in Women With CMD

Coronary Microvascular Dysfunction (CMD) occurs when there are problems in small blood vessels/arteries in the heart and symptoms of persistent chest pain that impact women. There are an estimated 3 million women in the US with CMD and about 100,000 new cases annually. This research will investigate whether the stress …

45 years of age Female Phase N/A
V Virginia Janovsky

Responsive Neurostimulation for Post-Traumatic Stress Disorder

Post-traumatic stress disorder (PTSD) refractory to treatment is marked by failure of fear extinction and its biological substrate, amygdala reactivity to trauma reminders. Decades of research have clarified the neuronal mechanisms coordinating fear extinction and consolidation. Fear cells and extinction cells in the basolateral amygdala (BLA) alter their firing rate …

25 - 60 years of age Male Phase N/A
S Stress and Resilience Research Labs

Cannabidiol (CBD) and Stress Response: Psychobiological Mechanisms

The aim of this study is to determine the effects of regular cannabidiol (CBD) use on the psychobiological mechanisms of the stress response. This will be achieved by comparing acute stress responses of adults who either use or do not use CBD regularly. Correlates of CBD use, including tobacco use, …

21 - 70 years of age All Phase N/A

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