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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 904 clinical trials
I Inés Contreras

Efficacy of Direct Selective Laser Trabeculoplasty in Clinical Practice in Patients with Glaucoma

Prospective, single-arm, single-center, non-randomized, non-comparative study including naïve patients attending our center diagnosed with glaucoma, who have been recommended treatment with direct selective laser trabeculoplasty (DSLT) by their ophthalmologist and who are under no hypotensive medication. DSLT treatment will be performed with the Voyager DSLT system; it will consist of …

18 years of age All Phase N/A
C Christopher LEUNG

Comparisons of NAD Precursors for Neuroenhancement in Glaucoma Patients

The goal of this clinical trial is to determine whether oral supplementation with different nicotinamide adenine dinucleotide (NAD) precursors can improve visual function in adults with primary open-angle glaucoma. The main questions it aims to answer are: Does daily oral administration of equimolar doses of nicotinamide riboside (NR), nicotinamide (NAM), …

18 years of age All Phase 2
F Francesco Oddone, Dott.

Clinical Evaluation of Visual Field Change in Glaucoma: an Assessment of Different Models of Progression

The purpose of this observational study is to collect over time a series of data in patients with glaucoma in order to evaluate different approaches in defining the progression of this pathology. These data will be collected in repeated visits over a 36-months follow-up period. At each visit, the COMPASS …

40 - 90 years of age All Phase N/A

NorMIGS - a Study of Micro-invasive Glaucoma Surgery

NorMIGS is a non-randomized clinical study of intraocular pressure lowering effect and complications after Preserflo microshunt implantation versus other types of glaucoma surgery. The study is conducted in the Department of Ophthalmology, Oslo University Hospital, Norway.

18 years of age All Phase N/A
J Janie Tay

Altered Non-Visual Photoreception in Patients With Glaucoma: Impacts on Sleep, Alertness, Mood, and Cognition

The goal of this study is to understand how light sensitivity in the eye affects sleep, mood, alertness, and cognition in adults with glaucoma compared to healthy individuals aged 45-75 years. The main questions it aims to answer are: Do patients with glaucoma experience poorer sleep, mood, alertness, and cognitive …

45 - 75 years of age All Phase N/A
Y Yu-Cen Ma, MS

Repetitive Transcranial Alternating Current Stimulation (rtACS) for the Treatment of Optic Neuropathies

The goal of this study is to see whether repeated transcranial alternating current stimulation can activate impaired retinal ganglion cells and improve both structural and functional outcomes in patients with glaucoma.

18 years of age All Phase N/A
h hassan lotfy fahmy, prof

Modified Trabeculectomy After Failure of Combined Phaco With GATT

These procedures include deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule.

21 - 70 years of age All Phase N/A
K KATRIN LORENZ

Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years

The purpose of this study is to evaluate the long-term effectiveness and safety of the Hydrus implant combined with concomitant phacoemulsification for lowering intraocular pressure (IOP).Glaucoma patients often have high intraocular pressures (IOP) and need long-term IOP control to prevent loss of visual function and blindness. To date, data on …

years of age All Phase N/A
K Kaijun Wang, MD

Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma

To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.

18 - 90 years of age All Phase N/A

Metformin as a Neuroprotective Therapy for Glaucoma

Glaucoma, a chronic degenerative disease of the optic nerve, is the leading cause of irreversible blindness worldwide. Although lowering the intraocular pressure (IOP) has been shown to be effective to slow optic nerve degeneration, a significant portion of glaucoma patients continue to develop progressive loss in vision despite adequate control …

18 years of age All Phase 2

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