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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 891 clinical trials
S Stephen Juraschek, MD, PhD

Wearable Evaluation of Ambulatory Readings for Blood Pressure

The purpose of this project is to compare the performance and validity of novel wearable technologies that measure blood pressure (BP) and physical activity with a Spacelabs Ambulatory Blood Pressure Monitoring (ABPM) device.

18 - 100 years of age All Phase N/A

Phase III Study to Evaluate the Efficacy and Safety of AD-209

The purpose of this study is to evaluate the efficacy and safety of AD-209

19 years of age All Phase 3

A Study to Evaluate the Efficacy and Safety of AD-224

The purpose of this study is to evaluate the efficacy and safety of AD-224

19 years of age All Phase 3
C Chongyuan Xu, Ph.D

SAL0140 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population

The purpose of this study is to evaluate the safety, tolerability pharmacokinetics and pharmacodynamics of SAL0140 healthy Chinese population.

18 - 65 years of age All Phase 1

JX09 SAD/MAD in Healthy Participants

This is a phase 1, randomized, double-blind, placebo-controlled, multi-part, single and multiple ascending dose study in healthy adult to test the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of JX09 when administered to healthy adult subjects.

18 - 55 years of age All Phase 1
J Julie Etheridge

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 OUS Study)

Characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Group 2 Pulmonary Hypertension

22 - 85 years of age All Phase N/A

Preliminary Human Trials of F230 Tablets

F230 is a new Class 1 chemical drug jointly developed by Beijing Contini Pharmaceutical Co., Ltd. for the treatment of pulmonary hypertension (Notification number: 2024LP01242, 2024LP01243). The in vitro activity and in vivo toxicology tests of F230, the lead compound for the treatment of PAH developed by Beijing Contini Pharmaceutical …

18 - 45 years of age All Phase 1
J Jane Gillespie, RN

Bioenergetic Effect of Pioglitazone in CLD-PH

The goal of this clinical trial is to learn about the safety and efficacy of Pioglitazone in people with Pulmonary Hypertension (PH) due to Chronic Lung Disease (CLD). The main question it aims to answer is: • Whether pioglitazone affects mitochondrial oxygen utilization in patients with PH due to CLD. …

18 years of age All Phase 2
R Rebecca Stone, MPH

Sequential Multiple Assignment Randomized Trial to Reduce Food Insecurity

Food insecurity affects 20% of the 116 million people in the US with hypertension and is associated with poor adherence to evidence-based treatments and disparities in hypertension outcomes. Interventions are being used to address food insecurity in clinical care settings, but people differ in the support they need to reduce …

18 years of age All Phase N/A
M Maria El-Hachem

Renal Pelvic Denervation Pilot Trial

The RPD Pilot trial will evaluate the safety and effectiveness of Verve Medical's RPDTM renal denervation system for hypertensive patients with uncontrolled blood pressure despite use of two medications at a therapeutic dose. The novelty of the RPDTM system relates to its placement via natural orifice into the renal pelvis …

21 - 80 years of age All Phase N/A

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