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high-blood-pressure Clinical Trials

A listing of high-blood-pressure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 891 clinical trials
J Job van Steenkiste, MD, MsC

Telemonitoring and E-Coaching in Hypertension

Rationale: Hypertension is the most significant risk factor for cardiovascular disease and can be mitigated by lifestyle and medical management. Telemonitoring as a novel management approach to perform hypertension management at distance has been thriving but became indispensable during the COVID-19 pandemic. However, evidence of an effective implementation for telemonitoring …

18 years of age All Phase N/A
X Xin Zheng, MD,PhD

Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension

In this multicenter, randomized, placebo-controlled trial in pre-heat failure patients with hypertension and without diabetes, we will enroll 120 eligible patients to randomized to receive placebo or engagliflozin (10mg/d) for follow them for 6 months. The primary endpoint is the left atrial volume index, which reflects left ventricular diastolic function. …

40 - 75 years of age All Phase 4
J John Ko, M.Sc

Stretching vs Walking for Lowering Blood Pressure

High blood pressure is a leading risk factor for cardiovascular disease. Traditionally, one of the ways to treat or prevent high blood pressure is to prescribe aerobic exercise training (i.e. brisk walking). Stretching may also be effective because it may cause changes in blood vessel stiffness and therefore reduce resistance …

18 years of age All Phase N/A

Immediate Pressor Response to Oral Salt

The goal of this study is to establish a diagnostic accuracy of an immediate pressor response to oral salt (IPROS) to identify salt sensitivity of blood pressure (SSBP)

18 - 50 years of age All Phase N/A
M Mariam Attia, RPh

The Effect of Pharmacist-Initiated Home Blood Pressure Monitoring on Blood Pressure Control in Women

To evaluate the impact of home blood pressure monitoring when used in addition to pharmacist care, compared to usual care, in women with elevated blood pressure (BP). Randomized 1:1 two-arm controlled trial. Patients to be identified and screened by pharmacists. Patients with a BP >140/90mmHg or >130/80mmHg in those with …

18 years of age Female Phase N/A
L Linda Betz, Dr.

Effectiveness of a Digital Health Application for Primary Hypertension (Liebria)

This clinical trial with 328 patients with primary hypertension aims to investigate the effectiveness of the self-guided digital application liebria for patients with primary hypertension.

18 years of age All Phase N/A
R Richard Metcalfe, PhD

Isometric Handgrip Training Frequency and Blood Pressure in People With Hypertension

Hypertension is the most important cause of cardiovascular disease (CVD), stroke, and premature death (WHO, 2021). It is estimated by The World Health Organisation in 2021 that 1.4 billion individuals across the globe have high blood pressure, with only 14% of people actively managing these elevated levels. Simple and effective …

18 - 65 years of age All Phase N/A

Effect of Isometric Handgrip Training on Ambulatory Blood Pressure in Patients With Hypertension

Meta-analysis studies have demonstrated that isometric training with handgrip promotes reductions in clinical blood pressure, reaching 8 mmHg for systolic blood pressure and 4 mmHg for diastolic. However, the effects of this training modality on ambulatory blood pressure, which is better discriminant of cardiovascular risk than clinical BP, remains uncertain. …

18 years of age All Phase N/A
M Mario Funes Hernandez, M.D.

Technology-enabled Management Versus Usual Care for Blood Pressure

Two arm parallel randomized clinical trial

30 - 90 years of age All Phase N/A
Y Ying Wang

VB19055 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population

The purpose of this study is to evaluate the safety,tolerability,pharmacokinetics and pharmacodynamics of VB19055 in the healthy Chinese population.

18 - 50 years of age All Phase 1

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