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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 221 clinical trials
A Alexander Franz, B.Sc.

Impact of Different Perioperative Tourniquets on Blood Loss and Surgeon Satisfaction in Total Knee Arthroplasty

The present study investigates the impact of two different perioperative tourniquets with different closing features on operative blood los, surgical field quality and surgeon satisfaction.

18 years of age All Phase N/A
C Chengli Yan

Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation

This study conducts clinical experiments on the form, temperature, frequency and other issues of cooling therapy, so as to provide scientific evidence for the practice of cooling therapy and improve the comfort and effect of cooling therapy, so as to achieve the goal of improving service and patient experience proposed …

18 years of age All Phase N/A

Intraosseous (IO) Cefazolin and Vancomycin in Primary Total Knee Arthroplasty (TKA)

The goal of this clinical trial is to compare the efficacy of intravenous (IV) and intraosseous (IO) antibiotic administration techniques during primary total knee arthroplasty (TKA) in adults undergoing a TKA procedure at Houston Methodist Hospital. The main questions it aims to answer are: Does IO administration of vancomycin and …

18 years of age All Phase 1/2
I Ina Callebaut, PhD

BLOCK-study: Better Local Orthopedic Pain Control After Knee Arthroplasty

The goal of this study is to compare the anesthetic combination iPACK with femoral triangle block versus surgical LIA for unilateral TKA. We hypothesize that an iPACK block with femoral triangle block is non-inferior to surgical LIA. Furthermore, due to visualization of the relevant neural and vascular structures, the risk …

18 - 85 years of age All Phase N/A
A Ayse DEMIRTAS

The Effect of Abdominal Massage and Warm Application on Excretory Activity in Patients Undergoing Total Knee Replacement With Spinal Anesthesia

The aim of this study was to determine the effect of abdominal massage and warm application on the excretory activity (time of first bowel sounds, defecation time and the amount of laxative used until discharge) after total knee replacement surgery performed with spinal anesthesia.

18 years of age All Phase N/A
D Didier MAINARD, Pr

Performance and Safety Evaluation of the FHK®-CK Knee Prosthesis

The life expectancy worldwide is increasing and leading to an increase of knee arthroplasty. Also, as millions of people around the world are currently living with a Total Knee Arthroplasty (TKA), the need for revision surgery represents a large public health burden. In this context, FH ORTHO company develops FHK®-CK …

18 years of age All Phase N/A

Postural Correctors & Activity Trackers in Total Knee Replacement Rehab

To assess the impact of postural corrector on post-operative knee function and activity To evaluate the role of activity tracker in monitoring and enhancing post-operative rehabilitation To assess the effects of postural corrector and activity tracker on pain management during rehabilitation

40 - 60 years of age All Phase N/A
K Kubilay Ekinci, MD

Comparison of Two Different Regional Anesthetic Methods in Total Knee Arthroplasty Patients

Total Knee Arthroplasty patients are among the orthopedic cases that experience severe postoperative pain. In these cases, pain must be controlled. If pain is not controlled, early mobilization cannot be achieved. This can result in delayed physical therapy, prolonged hospital stays, the development of nosocomial infections, and impaired cognitive function. …

18 - 75 years of age All Phase N/A

Effect of Walker vs Wheeled Device on Mobility After Total Knee Arthroplasty

Maneuverability is currently under appreciated by patients who are seeking mobility. This pilot study is examining how patients maneuverability and mobility will change with this novel mobility tool - A-Linker compared to the standard of care walker.

18 - 99 years of age All Phase N/A
H Hatice Merve Alptekin research assistant

Effect of Artificial Intelligence-Assisted Motivational Talk on Patients' Fear of Movement and Mobility Level After Knee Replacement

Patients may have fears about moving after TKA surgery. This fear has been described in the literature. Fear of re-injury has also been called kinesiophobia, which is the primary psychosocial structure in the fear-avoidance model. Injury or surgery can create feelings of uncertainty and fear of how much the injury …

18 years of age All Phase N/A

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