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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 550 clinical trials
L Lina Badimon, MD

International Survey of Acute Coronary Syndromes

The International Registry of Acute Coronary Syndromes registry study (ISACS) is both a retrospective and prospective study which was designed in order to obtain data of patients with acute coronary syndromes, and herewith control and optimize internationally guideline-recommended therapies in these countries

18 years of age All Phase N/A
S Sarah Albayrak-Rena

HIV-HEART Aging Study

The HIV/HEART Aging study (HIVH) is an ongoing, prospective, multicentre trial that was conducted to assess the incidence, the prevalence and the clinical course of cardiovascular diseases (CVD) in HIV-infected patients. The study population includes outpatients from specialized HIV-care units of the German Ruhr region, who were at least 18 …

18 years of age All Phase N/A
D Damini Dey, PhD

WARRIOR Ancillary Study for CCTA Analysis

In this study, quantitative characterization of plaque using coronary computed tomographic angiography (CTA) will be used to determine if women who were treated with intensive medical therapy have a greater reduction in the amount and type of cholesterol plaque compared to women receiving usual care and if this results in …

18 years of age Female Phase N/A
L Lei Jiang

Effect of PCI on Clinical Prognosis of Chronic Coronary Artery Occlusion

Coronary chronic total occlusions (CTOs) are considered to increase the risk of adverse clinical outcomes. The purpose of this study was to evaluate whether long-term clinical outcomes could be improved by successful percutaneous coronary intervention (PCI) over optimal medical therapy (OMT) in CTO patients.

18 - 75 years of age All Phase N/A

Postprandial Triglyceride Impact on Coronary Atherosclerosis in Non-Diabetic Patient in Sohag University Hospital

INTRODUCTION Cardiovascular diseases, including coronary artery disease (CAD), are the leading cause of mortality worldwide. Despite remarkable advancements in diagnostic and therapeutic approaches, CAD continues to pose formidable challenges. Atherosclerosis, characterized by the deposition of lipids, inflammatory cells, and fibrous tissue within the arterial walls, is the fundamental pathology underpinning …

years of age All Phase N/A
B Bon-Kwon Koo, MD, PhD

Relationship Between Coronary Angiography Findings and Fractional Flow Reserve After Balloon Angioplasty

The goal of this prospective observational study is to learn about in patients who need percutaneous coronary intervention for coronary artery disease. The main questions it aims to answer are: Fractional flow reserve according to coronary angiography findings after coronary artery balloon angioplasty Differences in fractional blood flow reserve before …

19 - 120 years of age All Phase N/A
A Aju Pazhenkottil

Complementary Investigation of Perfusion and Anatomy Measures of the Heart With MRI and Combined PET/MRI

The goal of this observational study is to evaluate the complimentary information of anatomy, perfusion and viability of PET and MR. The main question[s] it aims to answer are: to compare perfusion and anatomy measurements and perfusion related signals from PET and MR imaging and estimate its prognostic values. to …

18 years of age All Phase N/A
O Olivier CHARANSONNEY, MD

Evaluation of the Benefit of Exercise Testing for the Diagnosis of Obstruction in the Coronary Arteries of the Heart

The purpose of this study is to determine whether exercise testing can detect an obstruction in a coronary artery, and, thereby, can avoid performing a coronary imaging in some cases. Patients with a suspicion of coronary artery disease perform an exercise test on an exercise bike with increasing load. EKG, …

18 years of age All Phase N/A
M Mo Elshibly

CMR Versus CT in Coronary Artery Disease

CONCORD is a prospective observational study evaluating the diagnostic accuracy of cardiovascular magnetic resonance (CMR) and computed tomography with fractional flow reserve (CT-FFR) in patients with suspected coronary artery disease, using invasive fractional flow reserve (FFR) as the reference standard.

18 years of age All Phase N/A
S Sushanna Lai

BioFreedom Ultra Registry

Over the past three decades, coronary stent struts have been made progressively thinner. Thin strut drug-eluting stents (DES) performed better than their thicker counterparts in a recent study. Thinner struts discourage abnormal coronary flow after implantation and associated with greater flexibility, deliverability and better clinical outcomes. Lower strut thickness may …

18 years of age All Phase N/A

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