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Knee Replacement Clinical Trials

A listing of Knee Replacement medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 542 clinical trials

SUPRAFLEX CRUZ PMCF Study ( rEpic05 )

Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Medical Device Regulations (MDR) with multivessel coronary disease requirements in all the CONSECUTIVE patients treated with (SUPRAFLEX CRUZ).

18 years of age All Phase N/A
G Gregor Leibundgut, Prof

PCI Registry Basel

This registry aims to learn more about the best ways to treat coronary artery disease. Information from routine medical care will be collected to compare different treatment approaches, including drug-eluting stents, drug-coated balloons (DCB), and bioresorbable scaffolds (BRS), which gradually dissolve over time. The registry will include people with coronary …

18 years of age All Phase N/A
J Jiaojiao Pang, Doctor

MCG for Non-Obstructive Myocardial Ischemia

The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.

18 years of age All Phase N/A

Selective Coronary Revascularization in Peripheral Artery Disease Patients (SCOREPAD Trial)

The primary objective of this study is to determine whether among symptomatic Peripheral Arterial Disease (PAD) patients with no known Coronary Artery Disease (CAD) who had undergone lower-extremity revascularization, a strategy of best medical therapy (BMT) plus selective coronary revascularization based on FFRct assessment of lesion-specific coronary ischemia can reduce …

50 years of age All Phase N/A
H Hong Liu, MD

Factors Affect Outcomes in Cardiovascular Surgery

Identify factors that contribute to perioperative morbidity and mortality in patients undergoing cardiac surgery that involves cardiopulmonary bypass. Identify factors that affect perioperative morbidity and mortality in patients undergoing cardiac surgery.

18 years of age All Phase N/A
J Jinqing Yuan, MD

NOAC Therapy Guided by PARIS Risk Score and D-dimer in Patients With ACS After PCI

The goal of this clinical trial is to compare short-term Triple Antithrombotic Therapy (DAPT + Rivaroxaban) followed by DAPT with standard DAPT in selected ACS patients with high ischemic risk. The main questions it aims to answer are: Whether the intervention is effective in reducing ischemic events Whether the intervention …

18 - 75 years of age All Phase 4
E Elmir Omerovic, MD, Prof

STICH-3.0 International Trial Consortium

The primary objective of the STICH 3.0 Study is to determine whether CABG is superior to PCI in terms of all-cause mortality at 5 years in patients with severe CAD and iLVSD. Individual patient data from similar national RCTs independently powered for different efficacy endpoints will be pooled, harmonized, and …

18 years of age All Phase N/A
J Jia Zhou

CCTA Improves Clinical Management of Stable Chest Pain

The investigator aims to prospectively enroll patients who were referred for coronary computed tomography angiography (CCTA) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent CCTA according to established guidelines and local institutional protocols. The imaging data were evaluated using different …

18 years of age All Phase N/A
P Pál Maurovich-Horvat, MD, PhD, MPH

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

The clinical and demographic characteristics of patients undergoing transcatheter aortic valve implantation (TAVI) pose unique challenges for coronary computed tomography (CT) imaging, as this patient population is mainly composed of elderly, frail individuals with severe aortic stenosis, multiple comorbidities, high prevalence of heavily calcified coronary artery disease (CAD) and revascularized …

18 years of age All Phase N/A
X Xin Huang, PhD,MD

Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease

The IVUS-CKD study is a prospective, randomized controlled, multicenter trial to determine whether the intravascular ultrasound (IVUS)-guided percutaneous coronary intervention is superior to the angiography-guidance in chronic kidney disease (CKD) patients with respect to target vessel failure (TVF) at 12 months after randomization.

18 years of age All Phase N/A

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