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Dementia Clinical Trials

A listing of Dementia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 804 clinical trials
F Fred Ketchum, M.D., PhD

Evaluation of a Decision-Support Tool for Blood Biomarker Testing for Alzheimer's Disease in Primary Care

The goal of the current study is to evaluate a decision-support tool intended to help primary care providers (PCPs) communicate with patients about blood biomarker testing for Alzheimer's Disease, enhancing shared-decision making and information sharing in the clinical space. The main questions it aims to answer are: Is the decision-support …

50 years of age All Phase N/A
K Kaleigh Oberndorfer

Investigations of Dementia in Parkinson Disease

The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson disease (PD). The ultimate goal of this project is to be able to identify individuals with …

50 years of age All Phase N/A
J Jonathan D Singer, PhD

Improving Mental Health for Care Partners of Persons With AD/ADRD

The overarching goal of this project is to evaluate if evidence-based interventions can reduce PDG, burden, and stress in informal caregivers of individuals with dementia

18 - 120 years of age All Phase N/A
A Anna Soteras Prat

Personalized Brain Health Service and Dementia Prevention

This study evaluates the feasibility of implementing a Brain Health Service (BHS) to assess and reduce dementia risk in individuals with Subjective Cognitive Decline (SCD). A total of 120 participants will be recruited from the Cognitive Disorders Unit at Hospital del Mar and randomly assigned to either a personalized intervention …

55 - 85 years of age All Phase N/A

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease

This is a Phase 1b, multicenter, randomized, placebo-controlled, double-blind, multiple ascending dose (MAD) study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of DNL628 in participants with early Alzheimer's disease (AD), defined as mild cognitive impairment, or mild AD with biomarker evidence of amyloid positivity.

18 - 75 years of age All Phase 1
L Lin Ma

Evaluation of 611 in Chinese Children With Moderate to Severe Atopic Dermatitis(AD)

This study is a 2-part (parts A and B) study.The primary objective of the study is to evaluate the efficacy of 611 in Chinese Children with moderate to severe atopic dermatitis (AD).

2 - 11 years of age All Phase 3
Y Yuri Jang, PhD

Caring for Dementia Caregivers in Ethnic Immigrant Communities

Many caregivers of people with Alzheimer's disease or other dementias-especially those in immigrant communities who don't speak English well-don't get access to helpful, proven support programs. To address this, the investigative team adapted an existing caregiver support program (called the Savvy Caregiver Program) to better fit target group's culture and …

18 years of age All Phase N/A
C Chase Brice, B.S.

Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia

More than 15 million family caregivers provide support for individuals with Alzheimer's disease (AD) or related dementias. This number is expected to grow with the increasing population of persons with dementia (PWD). Stress in caregivers to older adults with chronic diseases is already a significant public health issue because it …

50 years of age Female Phase 2
L Li Pan, Director

Temporal Interference Stimulation Treatment in Patients With Cognitive Impairment

This study aims to evaluate the efficacy and safety of temporal interference stimulation (TIS), a non-invasive neuromodulation technique, in improving cognitive function in patients with cognitive impairment. TIS uses two high-frequency currents applied transcranially, which intersect within the brain to generate a low-frequency modulation field. This technique selectively modulates deep …

45 - 85 years of age All Phase N/A
A Arvid Rongve, Phd

ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB)

The goal of the study is to develop predictive algorithms and digital biomarkers to capture disease fluctuations in (prodromal) dementia with lewybodies (DLB) patients and to improve treatment, diagnosis and prognosis of the study drug Ambroxol, used in the ANeED study. This project is an additional study to the ANeED …

50 - 85 years of age All Phase N/A

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