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Colon Cancer Clinical Trials

A listing of Colon Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 214 clinical trials

Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection

The objective of this low-risk interventional study is to evaluate whether the PreveCol® test has sufficient efficiency to be considered as a second-line method for the detection of both colorectal cancer and advanced adenomas when used prospectively in the screening population with a previous positive FOBT result, which could include …

50 - 69 years of age All Phase N/A
M Mark C. Burgmans, Md, PhD

Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors

The endpoint of this study is to develop and validate algorithms, using artificial intelligence and machine learning, to optimize patient selection, treatment planning, treatment evaluation and outcome prediction in patients undergoing thermal ablation of a malignant liver tumor. The long-term objective is to establish thermal ablation as the treatment of …

18 - 110 years of age All Phase N/A
F Fiona Evans

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical trial enrollment (CTE), as well as the financial impact, …

years of age All Phase N/A
L Lauren Keppeler

Integrated Cancer Repository for Cancer Research

The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant …

19 - 110 years of age All Phase N/A

Tranexamic Acid During Colonic Endoscopic Resection Procedures

Colonoscopy with polypectomy reduces the incidence and mortality associated with colon cancer. However, polypectomy is associated with adverse events such as bleeding. Tranexamic acid (TXA) is a synthetic derivative of lysine that exerts antifibrinolytic effects and may prevent bleeding. The investigators aim to evaluate the effect of local TXA on …

18 years of age All Phase 4
Y Yurong Jiao

Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer

This study aims to elucidate the regression effects of neoadjuvant chemotherapy combined with immunotherapy and adjuvant therapy in locally advanced MSS colon cancer.

18 - 75 years of age All Phase 2
A Abigail Tice, Ph.D.

Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.

18 years of age All Phase N/A
G GAEL ROTH, MD, PHD

Tumor Immune Microenvironment Involvement in Colorectal Cancer Chemoresistance Mechanisms

Colorectal cancer is the third most common cancer worldwide and its progression-free survival is still low, around 10 months. Thirthy to 50% of patients do not respond to chemotherapy upon initiation of treatment, suggesting that early development of chemoresistance mechanisms remains a major challenge. In order to better characterize these …

18 years of age All Phase N/A
P Paul Reiter

Strategies for Optimizing a Mailed FIT Program in Appalachia

The proposed study is examining strategies for optimizing mailed fecal immunochemical test (FIT) programs. In doing so, it will assess the efficacy of two promising strategies, FIT kit materials and patient navigation delivery mode. These strategies may help to improve colorectal cancer screening rates.

45 - 74 years of age All Phase N/A
D David Ljungman, MD PhD

Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome

Multicenter, multinational, randomized, 2-arm, double-blind, phase II clinical study with 2000mg mesalamine, or placebo for prevention of colorectal neoplasia in Lynch Syndrome patients during and following daily intake for 2 years.

30 years of age All Phase 2

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