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Vascular Diseases Clinical Trials

A listing of Vascular Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 835 clinical trials
F Fiona Leahy, MSc

The Biomechanical Study of Diseased Human Carotid, Femoral and Abdominal Aortic Tissue

This cross-sectional study aims to ascertain the mechanical properties of human carotid/femoral atherosclerotic plaque and abdominal aortic aneurysm tissue and correlate tissue mechanics with novel blood-based biomarkers of cardiovascular calcification.

18 years of age All Phase N/A
Z Ziheng Wu, M.D.

Eluvia DES for the Patients With Femoropopliteal Artery Lesions.

This study is a multicenter, prospective, observational study, aiming to enroll 400 patients with peripheral arterial disease in the femoral-popliteal segment implanted with Eluvia stent. Each patient was followed up for 2 years. The technical success rate, target lesion patency rate, quality of life improvement, cost of Eluvia stent implantation, …

years of age All Phase N/A

Inflammation in Vascular Disease

Increasing evidence suggests that systemic low-grade inflammation may be a driving force of cardiometabolic complications, such as vascular dysfunction, atherosclerosis and ischemic heart disease. Thus, we will investigate the role of inflammation in cardiovascular disease.

18 years of age All Phase N/A
S Sharon Blohowiak

Mechanisms of Pregnancy Vascular Adaptations

The investigators will collect omental tissue (research surgical excision) and placental tissue (standard of care clinical delivery) from both preeclamptic and non-preeclamptic women during their c-section and use these samples to study the blood vessels, specifically the expression/activation of the AT2R.

18 - 40 years of age Female Phase N/A
M Michael Campos, MD

Early Detection of Vaping-related Vascular Diseases

The purpose of this study is to determine how vaping affects blood vessels, in particular if early damage occurs in the lung vessels.

18 - 40 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

Background Stroke is the fifth leading cause of death in the United States. It is also a leading cause of disability. More than 70% of people who survive strokes have mental impairment or dementia. Medical factors, such as the severity of the stroke, affect whether a person will have mental …

18 - 99 years of age All Phase N/A
E Edward Fox, BA

Diabetic Neuropathy in Spinal Cord Stimulator Patients

The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic neuropathy; we will evaluate improving their disability and quality of life, improving micro-circulatory changes induced by …

18 years of age All Phase N/A
J Joanne Burgess, RN

Studies of Neuregulin/ERBB Signaling in Human Heart

This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

18 years of age All Phase N/A
A Anna Bersano, MD

SEarchiNg biomarkErs Cerebral Amyloid Angiopathy (SENECA)

Cerebral amyloid angiopathy (CAA) is one of the major types of cerebral small vessel disease, and a leading cause of spontaneous intracerebral hemorrhage and cognitive decline in elderly patients. Although increasingly detected, a number of aspects including the pathophysiology, the clinical and neuroradiological phenotype and the disease course are still …

55 years of age All Phase N/A
K Katie Suriano

Hypertension Explored in Long-term Postpartum Follow-up in Later Life

The purpose of this study is to understand more about why women who have had hypertensive pregnancies may be at increased risk of high blood pressure and why these women are often at increased risk of heart and blood vessel disease later in life.

30 - 70 years of age Female Phase N/A

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