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Vascular Diseases Clinical Trials

A listing of Vascular Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 842 clinical trials
F Finn (Fiona) Fox, BS

Treatment of Orthostatic Hypotension in SCI

The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.

18 - 60 years of age All Phase 4

Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS

The goal of this study is to evaluate if a novel near-infrared spectroscopy (NIRS) device can accurately estimate blood pressure in newborns at risk for unstable blood pressure. The main questions it aims to answer are: Can NIRS accurately estimate blood pressure when compared to the gold standard, arterial line …

24 - 44 years of age All Phase N/A
Z Zhang Zhuan, professor

Venous Congestion and Cardiac Surgery-Associated Acute Kidney Injury

Venous pressure is often overlooked as an important hemodynamic parameter. Elevated venous pressure and blood stasis in organ tissues can lead to interstitial edema. Intraoperative venous blood stasis can rapidly increase interstitial pressures within organ tissues, especially in organs encapsulated by tissue envelopes, such as the kidney, thereby rapidly reducing …

18 years of age All Phase N/A
C Carlomaurizio Montecucco, MD

SysteMic vAsculitis pRognosis and ouTcome

This will be a pragmatic programme of research, consecutively recruiting all-comers who have been referred to secondary care for assessment of suspected Systemic Vasculitis (SV) into a longitudinal inception cohort. For patients with a pre-existing diagnosis, data on the disease onset will be collected retrospectively. All patients followed prospectively from …

18 years of age All Phase N/A
K Kathryn E Domanchuk, BS

Fisetin to Reduce Senescence and Mobility Impairment in PAD

The investigators propose a pilot randomized trial to gather preliminary data to test the hypothesis that Fisetin will reduce abundance of senescent cells in blood, skeletal muscle, and both subcutaneous and inter muscular adipose tissue and improve 6-minute walk distance in 34 people with peripheral artery disease (PAD). the investigators …

50 years of age All Phase 2
A Abele Donati, MD

Evaluation of the Microcirculatory Response to Fluids in Critically Ill Patients With Venous Congestion: A Prospective Observational Study

The hypothesis is that fluid-responsive patients who show signs of venous congestion experience a worsening of microcirculatory status after fluid administration compared to patients without signs of venous congestion

18 years of age All Phase N/A

Differential Regulation of RAAS-axis in Patients Undergoing Cardiac Surgery

This study investigates the question of whether there are differences in the plasma concentration of hormones of the RAAS-axis between patients undergoing on-pump cardiac surgery and those receiving off-pump surgery

18 years of age All Phase N/A
M Mustafa F Doctor

Evaluation of Fertitonex Effects on Semen Parameters in Clinical Varicocele Patient.

The aim of the study is to evaluate the Fertitonex effects on semen parameters in clinical varicocele patients.

18 years of age Male Phase N/A

Tocilizumab and Tofacitinib in the Treatment of Vascular Behçet's Syndrome

This project aims to evaluate the efficacy and safety of the combination of glucocorticoids with tocilizumab or tofacitinib, compared to the traditional combination of glucocorticoids with cyclophosphamide in the treatment of vascular Behçet's syndrome.

18 - 65 years of age All Phase 2

Multicenter Study to Evaluate the Effectiveness and Safety of Flow-Diverting Stents for Distal Intracranial Aneurysms

Using data obtained from the treatment of intracranial distal intracranial aneurysms with flow diverter, evaluate the effecy and safety of blood flow diverter for the endovascular treatment of distal intracranial aneurysms.

18 - 80 years of age All Phase N/A

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