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rectal-disorders Clinical Trials

A listing of rectal-disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 679 clinical trials
I Igor Monsellato, PhD

Neutrophil-to-Lymphocite Ratio (NLR) and C-reactive Protein (CRP) as New Markers in Diagnosis and Prediction of Colorectal Cancer

Colorectal cancer (CRC) is the second leading cause of cancer-related death in the Western world. Overall survival (OS) remains poor, with 50% estimated 5-year survival. In Italy, current estimates indicate that in 2020 a number of 43.700 patients have been affected by colorectal cancer, with an increasing of diagnosed cases …

18 years of age All Phase N/A

Multi-scale Spatio-Temporal Analysis of Research Data

MuSTARD is a singular project in the sense that investigators will develop a computational framework that is conceived as a common solution for disparate applications. This framework responds to a common need: the derivation of multi-scale spatio-temporal (ST) models equipped with statistical inference capabilities. Since the sequencing of the human …

18 - 90 years of age All Phase N/A
J Jin Gu, Prof.

A Predictive Model for Recurrence of Colorectal Cancer Based on Multi-omics of Portal Vein Blood

This multi-center study aims to develop a precise predictive model for colorectal cancer (CRC) recurrence and metastasis based on multi-omics analysis of portal vein blood. Despite advances in surgical treatments, approximately 40% of CRC patients experience tumor recurrence or metastasis post-surgery, with 80-90% of metastases being unresectable. The study will …

18 years of age All Phase N/A
K Khaled A Elsayed, Specialist

Colorectal Cancers :A Retrospective Study

Clinico-epidemiological and endoscopic characteristics of patients with colorectal cancers:A Retrospective study in Sohag The aim : determine the prevalence and clinicopathological pattern of patients with colorectal cancers interpretative association between risk factors and severity of patient condition to define possible predictors assess potential association between serum markers, imaging, endoscopic features …

18 - 80 years of age All Phase N/A

Role of Photon Counting CT in Detecting Liver Metastatis From Colorectal Cancer

Colorectal cancer is the first leading cause of cancer death in men and second in women. Its incidence rates also increased by 1%-2% annually in young adults (ages <55 years). The liver is the most common site of colorectal cancer metastasis, with approximately 25% 50% of patients developing liver metastases …

18 - 100 years of age All Phase N/A
M Meng Qiu, M.D.

A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients

This prospective, multi-center, real-world study is conducted to investigate the impact of different treatment strategies (systemic chemotherapy combined with oophorectomy or with other local treatment or chemotherapy alone) on the prognosis of ovarian metastatic colorectal cancer patients.

18 years of age Female Phase N/A

Observational Cross-reactivity Study for Colorectal Cancer Diagnosis

The objective of this observational study is to evaluate the false positive rate of the blood test based on molecular biomarkers and risk factors. A total of 250 patients diagnosed with various cancers and gastrointestinal diseases will be enrolled. The main question to be answered is Does the blood test …

18 years of age All Phase N/A

Patient-reported Outcomes (PRO) and Treatment Outcomes of Chinese Patients With MSS-type Advanced Colorectal Cancer Who Received the Zidovudine Combination Regimen in the Real World

The Chidamide + sintilimab ± bevacizumab regimen has become a post-treatment option for clinicians and patients after being included in the guidelines. The CAPability-01 study is a phase II RCT, with a limited number of enrolled subjects. Further observation of the safety and clinical real-world application status of the sidibemab …

18 years of age All Phase N/A
M Ms Aileen Duffton, PhD Cancer sciences

Advances in Imaging to Assess Response in Rectal Cancer

The goal of this observational study is to determine the feasibility of acquiring serial MRI images for advanced radiotherapy planning in colorectal patients. The main question it aims to answer: Is it feasible to acquire serial MR images for advanced radiotherapy planning for rectal cancer.

18 years of age All Phase N/A
A Annalisa Maroli, PhD

A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients

This study aims to investigate the clinical, socioeconomic, behavioral, genetic, and molecular factors characterizing Early Onset Colorectal Cancer (EOCRC) patients compared with Late Onset Colorectal Cancer (LOCRC) patients

18 years of age All Phase N/A

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