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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,181 clinical trials
Y Yeşim Aytur, Professor, MD

Magnetic Stimulation of Diaphragm in Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease characterized by persistent airflow limitation and respiratory symptoms due to airway and/or alveolar deterioration caused by severe exposure to harmful particles or gases and host factors. Exercise intolerance and decreased functional capacity develop as a result of the disorders …

18 years of age All Phase N/A
J Jinfu Xu, Doctor

A Study to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients with COPD

To evaluate the efficacy and safety of HL231 Solution for Inhalation vs Ultibro in Chinese patients with moderate to very severe COPD

40 years of age All Phase 3
J Jesus² GONZALES-EBERMEJO, Professor

Respiratory Support in Chronic Obstructive Pulmonary Disease (COPD) Patients

The hypothesis of this study is that any of 3 modalities of home non- invasive ventilation (NIV) compared to 'no NIV' (=hospital NIV) will reduce re-admission to hospital or death in COPD patients who remain persistently hypercapnic following an exacerbation requiring NIV.

18 years of age All Phase N/A
A Arthur Lemson, MD

Hypertonic Saline Inhalation for Mycobacterium Avium Complex Pulmonary Disease

The SALINE trial will investigate the effect of Hypertonic Saline inhalation plus best supportive care on burden of symptoms, clearance of mycobacteria and functional capacities in participants with Mycobacterium avium complex lung disease and compare the effect to treatment with best supportive care alone.

18 years of age All Phase 4
Y Young Ae Kang

Exercise Program in Patients With Nontuberculous Mycobacterial Pulmonary Disease

1.objective Evaluation of effectiveness and safety of exercise intervention program for patients with non-tuberculous mycobacterial pulmonary disease 2. background Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a chronic respiratory infection that generally affects individuals with structural lung diseases, such as chronic obstructive pulmonary disease (COPD) and bronchiectasis and without structural lung …

40 - 80 years of age All Phase N/A
R Robert Lafyatis, MD

Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis

The purpose of this study is to determine whether a regimen of high-dose immunoablative therapy will demonstrate safety that is consistent or improved with other published regimens in SSc patients, while maintaining a treatment effect.

8 - 60 years of age All Phase 2
M María Antonia Gómez-Mendieta, MD

Effect of Noninvasive Ventilation on Physical Activity and Inflammation in COPD Patients

Parallel, randomized and controlled clinical trial to evaluate the effect of 12 months of noninvasive mechanical ventilation versus conventional treatment in hypercapnic patients with stable COPD. Main objective: To evaluate the effect of 12 months of noninvasive ventilation on c-reactive protein concentration and daily physical activity in hypercapnic patients with …

45 - 75 years of age All Phase 4
N NATHANIEL MARCHETTI, D.O.

Biological Effects of Quercetin in COPD Phase II

This study determines whether quercetin supplementation reduces the inflammation and oxidative stress markers in patients with chronic obstructive pulmonary disease. It is small study with 8 subjects receiving quercetin 1000 mg/day, 8 patients receiving 500 mg/day and 4 subjects receive placebo.

40 - 80 years of age All Phase 2
W William Poncin

Ventilation Distribution in COPD Patients During Breathing Exercises

ELTGOL (Slow Expiration with the Opened Glottis in the Lateral posture) is an airway clearance technique performed in the lateral decubitus position. This technique focuses on optimizing ventilation of the infralateral lung (when the subject is lying in the lateral posture) to enhance local air-liquid interaction. Previous studies on ventilation …

40 years of age All Phase N/A
G Gang Hou, Professor

Safety and Efficacy of Endobronchial Valve for Bronchoscopic Lung Volume Reduction Surgery: a Prospective Pilot Study

The goal of this pliot study al is to preliminarily evaluate the effectiveness and safety of transbronchial lung volume reduction surgery using the self-devloped endobronchial valves for chronic obstructive pulmonary disease patients with emphysema phenotype . The main questions it aims to answer are: Does self-devloped endobronchial valves improve the …

40 - 85 years of age All Phase N/A

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