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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,040 clinical trials
R Robert J. Volk

CPRIT: Patient Adherence to Lung Cancer Screening

To understand participants' barriers to lung cancer screening and their experience with scheduling lung cancer screening.

50 - 80 years of age All Phase N/A
A Aurélie HAYOTTE, MD

Lung Ultrasound in Pediatric Acute Chest Syndrome

Sickle-cell disease is a common disease with serious complications, in particular acute chest syndrome (ACS), which can be life threatening. The pathophysiology of ACS is poorly understood, but alveolar hypoventilation appears to play an important role. Pulmonary ultrasound is increasingly used in pediatrics to diagnose ACS. The management of ACS …

1 - 17 years of age All Phase N/A
G Giuseppe Failla, MD

Environmental Pollutants in COPD and Lung Cancer

Epidemiological studies describe a statistically significant correlation between hospitalization rate and exposure to environmental pollutants such as atmospheric particulates (PM10 and PM2.5) and polycyclic aromatic hydrocarbons (PAH). Indeed, they induced the release of inflammation mediators and oxidative stress, involved in remodeling and destruction of the alveolar parenchyma, in turn associated …

18 years of age All Phase N/A
F Fabrizio Citarella, MD

A Study to Investigate the Family History of Cancer in Patients With Non-small Cell Lung Cancer (FAHIC - Lung).

Germline testing to find genetic alteration that can be linked to inherited susceptibility of developing the disease is recommended for patients diagnosed with certain solid cancers, such as breast, prostate and ovarian, due to strong association with inheritable mutations implying familiar counselling. Non-Small Cell Lung Cancer (NSCLC) is the leading …

18 years of age All Phase N/A
I Ivan Tancevski, MD

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils

Introduction: The etiology and therapy of eosinophilic lung diseases are still poorly understood. For individual forms of disease, such as eosinophilic asthma or eosinophilic granulomatosis with polyangiitis (EGPA), new therapeutic approaches exist that block the interleukin IL-5 or the IL-5 receptor. Eosinophilic manifestations of the respiratory tract can exclusively affect …

18 years of age All Phase N/A
O Oksana Kamenskaya, PhD, MD

Radiotherapy Exposed Lung Injury: Effect on Functioning - Cohort

Prospective cohort research to study the state of oxygen metabolism, reserve capabilities of cardiovascular and respiratory systems in patients with breast cancer to create a program of prevention and rehabilitation of lung damage in the process of complex treatment of the disease. The aim of the study is to study …

18 years of age Female Phase N/A
M Marion Maggi

Nitric Oxide Lung Diffusing Capacity in Systemic Sclerosis

To date, two devices to measure nitric oxide lung diffusing capacity (DLNO) are commercially available in Europe. Previous research has shown systematic between-device differences in lung diffusing capacity outcomes in healthy people (Radtke et al. ERJ Open Res. 2021 Sep 13;7(3)). The extent and magnitude of between-device differences in people …

18 years of age All Phase N/A
W Wei Dai

Shared Decision Making in Patients With Lung Cancer

The objective of this study is to develop a Decision Aid for Lung Cancer Molecular Testing (DA_LCMT) and to facilitate shared-decision making in patients who were diagnosed with lung adenocarcinoma by intraoperative frozen pathology about whether to conduct the molecular testing.

18 years of age All Phase N/A
A Adrienne Scott

Evaluation Of The Lung Microbiome In NTM Bronchiectasis

A biomarker cohort study design is proposed to study whether specific airway microbiota alterations are associated with pulmonary Non-tuberculous mycobacteria (NTM) disease. In a cohort of 200 subjects suspected of having pulmonary NTM disease, the investigators will evaluate the airway microbiome using an aliquot of the induced sputum and upper …

18 years of age All Phase N/A
J Jon Silversides

CMR Right Ventricular Contractile Reserve Following Lung Resection

Feasibility study investigating CMR dobutamine stress testing before and after lung resection

18 years of age All Phase N/A

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