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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,207 clinical trials
J Jenna Wong, MSc

Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant

This study is designed to characterize the changes in diaphragm structure, function and biology during bridging to lung transplant by mechanical ventilation or extracorporeal life support.

18 years of age All Phase N/A
Ł Łukasz Gąsiorowski, Prof

Influence of Postoperative Bronchoscopy on Pulmonary Complications After Anatomical Lung Resections.

Respiratory complications are the largest group of complications following anatomical lung resections. Most of these complications result from a disrupted evacuation of respiratory secretions. At present, prevention of such complications involve: aspirating of secretions with a catheter during surgery through an intubation tube, active postoperative rehabilitation, mucolytic treatment and effective …

18 - 89 years of age All Phase N/A
T Tobias Werther

Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants

To assess whether stepwise oxygenation-guided lung recruitment at regular intervals reduces the oxygen saturation index (OSI = Mean Airway Pressure × Fraction of inspired Oxygen × 100 / peripheral Oxygen Saturation, OSI = MAPxFiO2x100/SpO2) averaged over high frequency oscillation ventilation (HFOV) time in extremely preterm infants.

- 8 years of age All Phase N/A
C Chris Roberts

A Study of Post COVID-19 Mechanisms for Chronic Lung Sequelae

The purpose of this study is to understand why some people experience long term effects, such as shortness of breath and fatigue, after a severe COVID-19 infection

18 years of age All Phase N/A
L Linda Karnay

Using ctDNA to Detect Minimal Residual Disease After Lung Cancer Resection

ctDNALung-Detect is an investigator-initiated single arm, multi-institution study designed to assess the ctDNA detection rate and its association with Relapse Free Survival (RFS) in operable stage T1-T4 (T3,T4 multifocal) N0M0 non-small cell lung cancer (NSCLC) patients.

18 years of age All Phase N/A
J Jason Woods, PhD

Use of Hyperpolarized 129Xe MR Lung Imaging in Adults for Calibration

The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.

18 years of age All Phase 1/2

The Effect of Beta-glucan in Non-Small Cell Lung Cancer

The purpose of this study is to determine how beta-glucan affects the immune system in subjects with non-small cell lung cancer.

18 years of age All Phase N/A

Couple-Based Meditation for Metastatic Lung Cancer Patients and Their Partners

Objectives Our specific aims are to: Aim 1: Examine the feasibility of a couple-based meditation program in 50 patients with metastatic lung cancer and their partners. Aim 2: Establish the initial efficacy of a couple-based meditation program in patients and their partners regarding physical, psychological, and spiritual quality of life …

18 years of age All Phase N/A
G GEECHEN CHANG, MD, PhD

Development and Clinical Validation of Early-stage Lung Cancer Prognostic Kit

Lung cancer is the leading cause of cancer mortality worldwide in spite of the advanced progresses in medication and low-dose CT screening. The early-stage lung cancer accounts for less than 50% of newly diagnosed lung cancer in Taiwan, even in stage IB patients proximately 30% still suffer from recurrence and …

20 years of age All Phase N/A
O Oscar Arrieta, MD MSc

Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer.

The goal of this interventional phase III clinical trial is to evaluate objective intracranial response rate (iORR) after a treatment with total cranial radiation therapy plus concomitant transdermal nitroglycerin (NTG) addition or total cranial radiation therapy only in patients with stage IV non-small cell lung cancer with brain metastases and …

18 - 85 years of age All Phase N/A

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