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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,189 clinical trials
F Francisco de la Gala, MD, PhD

Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery

The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and postoperative complications. We will conduct a randomized, controlled, and blinded study in 177 patients with three arms: Control Group: …

18 years of age All Phase 4
M Marga Rominger, Prof MD

Ultra Low Dose CT and Use of Iomeron 400 in PCD-CT

Evaluation of ultra low dose protocols and Iomeron 400 contrast in PCD-CT

18 years of age All Phase N/A
R Russell Richardson, Ph.D.

: Vascular Function in Health and Disease

Many control mechanisms exist which successfully match the supply of blood with the metabolic demand of various tissues under wide-ranging conditions. One primary regulator of vasomotion and thus perfusion to the muscle tissue is the host of chemical factors originating from the vascular endothelium and the muscle tissue, which collectively …

18 years of age All Phase 1
C Catalina Lopera, MSc

Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease

According to the Pan American Health Organization (PAHO), chronic, non-communicable diseases (NCDs) are the main cause of death and disability in the world. The term, NCD refers to a group of diseases that are not primarily caused by acute infection and result in long-lasting health consequences, with significant long-term care …

60 - 90 years of age All Phase N/A
L Lian Yang

Decoding the Association of Imaging and Tumor Microenvironment in Lung Cancer Using Radiogenomic Approach(Radiogenomics-Lung)

This is the prospective, observational cohort study (Radiogenomics-Lung), which aims to explore the relationship between the imaging information of lung cancer patients, tumor microenvironment and the prognosis of lung cancer patients.

18 years of age All Phase N/A
X Xing Zhang, Professor

An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors

This study was a phase I safety and tolerability clinical trial conducted in a single-center, open-label, 3+3 design with dose escalation.

18 - 75 years of age All Phase 1
L Linzee Mabrey, MD, MSc

Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients

Hospitalized patients with ARDS will be randomized to intravenous treatment with a monoclonal antibody against CD14, called IC14, or placebo. They will be followed for 28 days. The primary outcome is the day 4 oxygenation index assessed as a continuous measure.

18 years of age All Phase 2
s sun yuting Dr

A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation

Sepsis is a systemic inflammatory response syndrome triggered by infection, and it is a common critical illness in clinical practice, often leading to multiple organ dysfunction. Among these, acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are among the most severe complications. The mortality rate of sepsis-related lung …

18 years of age All Phase 2/3
P Pietro Bertoglio, MD

Insights on Dissemination of Lung Cancer

In patients with resectable NSCLC treated with surgery alone or with surgery as part of a multimodal treatment; CTC, ctDNA, STAS, and lymph node micrometastasis levels will be evaluated to see if they are associated with recurrence patterns and long-term outcomes.

18 years of age All Phase N/A
L Lisa Fitzgerald

Immunoprevention for High-risk Lung Lesions

The main purpose of this study is to assess nadunolimab as an immunoprevention strategy for high-risk lung nodules in participants who are current or former tobacco smokers. The study may last up to 5 years for each participant.

18 years of age All Phase 2

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