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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,207 clinical trials

Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in COPD-patients

Airway resistance will be measured using the forced oscillation technique (FOT). The parameters Rrs, Xrs, and ∆Xrs will be compared before and after a pulmonary rehabilitation cycle at moderate altitude. Additionally, the differences between low and moderate altitude will also be examined.

18 years of age All Phase N/A
I Iram Nawaz, Mphill

Effects of Benson's Relaxation and Tai Chi in COPD

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disorder that significantly impacts respiratory function and quality of life. As COPD patients often experience symptoms such as dyspnea, fatigue, and anxiety, non-pharmacological interventions like Benson's Relaxation Technique and Tai Chi are gaining attention for their potential benefits in managing these …

40 - 50 years of age All Phase N/A
A Arjumand Bano, MS-CPPT

Combined Effects of Transcutaneous Electrical Diaphragmatic Stimulation With ACBT'S in Copd

The combined effects of transcutaneous electrical diaphragmatic stimulation (TEDS) and active cycle of breathing techniques (ACBTs) in patients with chronic obstructive pulmonary disease (COPD) conducted as a randomized controlled trial at Gulab Devi Hospital, the study involved 50 participants aged 40 to 60 with mild to moderate COPD. Participants were …

40 - 60 years of age All Phase N/A
E Else ter Haar, MD

PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action

Chronic dyspnea is the most characteristic symptom of patients with Chronic Obstructive Pulmonary Disease (COPD), with intermittent increases during exercise and other events.Despite optimal standard therapy, episodic dyspnea is a common occurrence in COPD. Recently, the PEP buddy was developed which is an easy-to use, hands-free device that generates positive …

40 years of age All Phase N/A
N Nicolas GUIBERT, MCU-PH

Trial Evaluating the Rate of Pneumothorax in Severe Emphysema Secondary to Endoscopic Volume Reduction With Two-stage ZEPHYR® Valves Versus Endoscopic Volume Reduction With One-stage ZEPHYR® Valves

Chronic obstructive pulmonary disease (COPD) affects 3.5 million people and is the third leading cause of death worldwide. Emphysema involves air retention in the lungs and is ultimately responsible for a major deterioration in the quality of life. Available drug treatments have moderate efficacy whereas surgical lung volume reduction can …

35 - 80 years of age All Phase N/A
C Celso RF Carvalho, PhD

Impact of Remote Vital Signs Monitoring in People Using Long-term Oxygen Therapy

Assess quality of life of patients using prolonged oxygen therapy

18 - 85 years of age All Phase N/A
I Isabella Drachmann, MSc.

GRACE - Graduated Response for Advanced COPD With Enhanced Support

The aim of this study is to explore the feasibility and potential for a positive impact of a graduated response for advanced COPD with Enhanced Support. The study is a randomized controlled trial of: systematic needs assessment advance care planning crossectoral virtual conferences. Researchers will compare quality of life and …

65 years of age All Phase N/A
E Elisabeth Bendstrup, Professor

The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility

In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the movement of the diaphram. The diaphragm is the muscle used for breathing between the …

18 years of age All Phase N/A

Impact of Long-acting Bronchodilator- -Corticoid Inhaled Therapy on Ventilation, Lung Function and Breathlessness

Multicentre, prospective, non-randomised, single-arm, open label, mechanistic study to investigate the mechanism of action of BGF 160 on ventilation pattern complexity and variability

40 - 75 years of age All Phase 1/2
W Wytze de Boer

Ultrasound of the Diaphragm Excursion Ratio as Physiological Biomarker in Acute Exacerbations of Chronic Obstructive Pulmonary Disease

3.1 Introduction and rationale In 2020 an estimate of 562.700 people had Chronic Obstructive Pulmonary Disease (COPD) in the Netherlands, resulting in 21.335 hospital admissions.\[1\] An acute exacerbation COPD (AECOPD) in combination with hospital admission is associated with high mortality and morbidity. \[2\] Noninvasive ventilation (NIV) has been very effective …

18 years of age All Phase N/A

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