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Lung Disease Clinical Trials

A listing of Lung Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 3,207 clinical trials
C Clinical Trial Referral Office

Insomnia in Patients With Metastatic Lung Cancer

This study evaluates how common insomnia (difficulties with sleep) is in patients with lung cancer that has spread from where it first started (primary site) to other places in the body.

18 years of age All Phase N/A

Biological Investigation of Explanted Endobronchial Lung Valves Study

Rationale COPD is a severe, often progressive and currently incurable lung disease which affects both the upper airways (chronic bronchitis) as well as the lower airways (emphysema). In advanced stages of the disease air-trapping severely reduces the ability to breathe and subsequently the quality of life. A highly effective treatment …

years of age All Phase N/A
O Oscar G Arrieta Rodriguez, M.D., M.Sc.

Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

The goal of this observational study is to describe the prevalence of germ line-pathogenic variants in Mexican patients with lung adenocarcinoma. The main questions it aims to answer are: What is the prevalence of pathogenic variants in genes associated with lung adenocarcinoma in Mexican patients younger than fifty? Which clinical-pathological …

16 - 85 years of age All Phase N/A
J Jesper M Magnusson, MD, PhD

Liquid biopsiEs fOr luNg AllogRaft Damage classificatiOn - LEONARDO

LTx has the shortest survival of all solid organ transplants. The complex and time-demanding diagnostics of allograft dysfunction are a significant reason for this. The current study aims overarchingly to improve survival after lung transplantation (LTx) through precise and fast diagnostics. The specific aim is to develop direct-to-clinical implementation biomarkers …

18 years of age All Phase N/A

Pulmonary Rehabilitation for Rural Patients With COPD

The purpose of this study is to test the uptake, effectiveness, and patient-caregiver-provider experience of a crucial treatment not provided in rural areas: pulmonary rehabilitation.

40 years of age All Phase N/A
O Oleksa Rewa, MD

Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients

This protocol describes a randomized controlled feasibility vanguard study designed to investigate the implementation and effects of esophageal pressure-guided positive end-expiratory pressure (PEEP) titration in patients with high body mass index (BMI) mechanically ventilated patients at the Edmonton Zone. The study will enroll 30 patients with body mass index (BMI) …

18 years of age All Phase 2
D Deping Zhao, MD, PhD

Comparison of Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm

This study aims to evaluate the superiority in recurrence-free survival of lobectomy compared with segmentectomy in patients with lung adenocarcinoma ≤ 2 cm with micropapillary and solid subtype positive by intraoperative frozen sections.

20 - 79 years of age All Phase N/A
T Thibault Parent, Dr

Investigating aCute heArt failuRe Decongestion Guided by Lung UltraSonography

The goal of this clinical trial is to investigate whether a lung ultrasonography (LUS)-guided decongestion strategy in adults hospitalized for acute heart failure (AHF) can improve patient-centered outcomes. The main questions it aims to answer are: Does this strategy shorten the length of stay and reduce early hospital readmissions? Does …

18 years of age All Phase N/A

Cryoprobe Biopsy and Chronic Rejection in Lung Transplant Recipients

The goal of this clinical trial is to evaluate which biopsy collection method helps to better diagnose rejection and relevant pathologic findings in lung transplant recipients. The main questions it aims to answer are: Does the 1.1 mm cryoprobe or the biopsy forceps provide better quality samples of lung tissue …

18 - 99 years of age All Phase N/A
S SiWei Bao

SSGJ-707 in Advanced Non-Small Cell Lung Cancer

This trial is a Phase III study. All patients are stage IIIB/C (unsuitable for radical therapy) or IV non-small cell lung cancer(NSCLC), Eastern Cooperative Oncology Group (ECOG) performance status 0-1. The purpose of this study is to evaluate the efficacy and safety of SSGJ-707 comparing Pembrolizumab in subjects with advanced …

18 years of age All Phase 3

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