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Breast Cancer Clinical Trials

A listing of Breast Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,198 clinical trials
S Samuel J Haryono, MD

Predicting BReast cAncer Response to neoadjuVant Therapy by ctDNA Assessment

This is a prospective and observational study, aiming to determine the detection rate and change of CtDNA in blood samples of cancer patients before, during and after neoadjuvant treatment. Determine the rate of ctDNA positivity at the time before treatment, Determine the rate of ctDNA positivity at the time during …

18 years of age Female Phase N/A

Per-Operative Radiotherapy by Papillon +TM in Localized Breast Cancer

Phase II study; open recruitment, multicentrique. The aim of this clinical research is to evaluate faisability and toxicity of the per-operative radiotherapy using PAPILLON + TM device for localized breast cancers patients over 65 years.

65 years of age Female Phase 2
A April Riddle, BSRT

Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI

The purpose of the study is to see if using an investigational drug called \[18F\]FMISO with PET/MRI imaging can help monitor and predict the effect of trastuzumab (Herceptin) on chemotherapy in patients diagnosed with advanced HER2 positive breast cancer. This study is for imaging purposes only and is not a …

18 years of age Female Phase 1
R Robin Dowell

Study of Screening Brain MRIs in Stage IV Breast Cancer

The study is a single arm, nonrandomized phase II prospective study, with the goal of investigating the role of screening brain MRIs in neurologically asymptomatic patients with metastatic breast cancer.

18 years of age All Phase N/A
K Katarzyna Jerzak, MD

Using a Blood Test to Monitor Metastatic Breast Cancer Treatment

The goal of this observational study is to assess the effectiveness of the mDETECT breast cancer blood test at monitoring treatment response in women with metastatic breast cancer undergoing treatment.

18 years of age Female Phase N/A
Y Yen-Ting Liu

Hypofractionated Radiotherapy With Concomitant Tumor Bed Boost for Breast Cancer

Hypofractionated breast radiotherapy with concomitant tumor bed boost for early breast cancer or ductal breast carcinoma in situ after partial mastectomy

20 - 85 years of age Female Phase N/A
z zhigang chen

Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast Cancer

Malignant hydrothorax and ascitic fluid in advanced breast cancer often arise from metastasis to the lungs, pleura, or liver. Patients with this condition experience rapid disease progression and multidrug resistance, facing limited treatment options. Clinical guidelines offer various therapies based on molecular subtypes; however, their effectiveness can be hindered by …

18 - 70 years of age All Phase N/A
M Maria Thomas, M.D., Ph.D.

Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer

In breast cancer patients with nodal involvement, numerous studies have demonstrated that adjuvant radiation therapy reduces the risk of local recurrence, regional recurrence, and distant metastases, in addition to improving survival. The dose and fractionation for adjuvant breast radiation therapy has evolved over time, as novel schedules have been compared …

18 years of age Female Phase 2

FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer

Several studies have shown improved sensitivity of FDG-PET/CT compared with conventional imaging for diagnosing metastatic breast cancer in retrospective and smaller prospective studies. For response monitoring, we expect FDG-PET/CT to detect disease progression earlier than CT in patients treated for metastatic breast cancer, enabling earlier start of second-line therapies. Current …

18 years of age All Phase N/A
J Justun Holder

Patient Priorities for Survivorship Care in Older Breast Cancer Survivors

The objective of this study is to adapt the Patient Priorities Care (PPC) framework to breast cancer survivorship via a user-centered approach, through an iterative process in which patients and their physicians help to refine and modify the intervention. A second objective is to evaluate the feasibility and effectiveness of …

65 - 100 years of age Female Phase 2

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