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hematologic-cancer Clinical Trials

A listing of hematologic-cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 342 clinical trials
B Bruce F. Sabath

The Impact of COVID-19 on Pulmonary Procedures

This study investigates the changes in practice by pulmonary procedural programs across the United States as they faced the coronavirus pandemic. Information gathered from this study may help guide pulmonary programs on a wider scale and improve their practice. The study may also help researchers understand where they should focus …

years of age All Phase N/A

Solving Riddles Through Sequencing

During the last decades hematologists have excelled at improving and refining the classification, diagnosis, and thus ultimately the therapeutic decision-making process for their patients. This continuous evolution proceeded in parallel to seminal discoveries in basic science such as FISH, PCR and NGS. So far, the current WHO classification serves as …

18 - 99 years of age All Phase N/A

oGVHD After Bone Marrow Transplantation: a Territory-wide Cohort

Allogeneic Haematopoietic stem cell transplantation (HSCT) is an effective treatment for all array of blood or blood-producing organ disorders. Graft-versus-host-disease (GVHD) occurs as a result of an overactive immunological system against normal host tissues. It can happen in the liver, skin, mucosal surface of the eye, gastrointestinal tract, and genitalia. …

18 years of age All Phase N/A
L Lærke Tolstrup, PhD

A Multi-center Investigation of Family Health.

The current healthcare system is unable to identify burdened and vulnerable families affected by cancer, partly due to a lack of knowledge of how cancer affects family health during treatment and survivorship. Recent reviews have documented a general lack of cancer studies including both the patient and the family, and …

18 years of age All Phase N/A
H Hafid AIT-OUFELLA, Professor

Early Assessment of Cardiac Function After Treatment With CAR-T Cells

CAR-T cells (Chimeric Antigen Receptor) are a new immunotherapy, based on the genetic modification of autologous T lymphocytes. CAR-T cell therapy is not devoid of complications. Among the most frequent complications are the risk of infection, cytokine release syndrome (CRS) and neurotoxicity. Nevertheless, some authors have reported serious acute cardiac …

18 years of age All Phase N/A
J Jeffrey J. Bruno

Impact of Aminoglycosides in Hypotensive Septic Oncology Patients

This study evaluates the impact of aminoglycosides in hypotensive septic oncologic patients. In the oncologic patient population, sepsis is a major health concern due to high mortality rates and healthcare costs. Prior research shows aminoglycosides antibiotics are frequently used to treat sepsis, but their clinical impact in hypotensive oncology patients …

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Background Bruton s tyrosine kinase inhibitors (BTKi) are used to treat a form of leukemia. But taking BTKi can also increase a person s risk of developing an abnormal heart rhythm. This can cause sudden death. In this natural history study, researchers want to learn how BTKi affects the heart. …

18 - 110 years of age All Phase N/A

Clinical Impact of Thoracic Scanographic Characteristics of Hematologic Malignancy Patients

The mediastinum can be the site of benign or malignant tumors, including 10 to 20% of hematological malignancies. Mediastinal mass syndrome (MMS) includes symptoms due to irritation, invasion or compression of the organs of the mediastinum. This syndrome includes respiratory manifestations that may be secondary to compression of the tracheobronchial …

16 years of age All Phase N/A
M Marie-Bérengère, TROADEC

Optical Genome Mapping in Hematological Malignancies

Establish the diagnostic potential of optical genome mapping in patients with suspected hematologic cancer

years of age All Phase N/A
C Courtney Schepel

Pre-malignant States to Hematologic Malignancies in Firefighters

The purpose of the study is to evaluate if firefighter exposure to hazardous compounds will increase the incidence of premalignant hematological states which subsequently increases the risk of the development of hematologic malignancies, and potentially other pathophysiological consequences.

40 - 49 years of age All Phase N/A

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