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Benign Prostatic Hyperplasia Clinical Trials

A listing of Benign Prostatic Hyperplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 84 clinical trials
Y Yusuf Gökkurt, MD

Impact of Long-term Dutasteride Use on Perioperative Outcomes of HoLEP

This study aims to investigate the effects of long-term dutasteride use (a 5-alpha reductase inhibitor) on surgical outcomes in patients undergoing Holmium Laser Enucleation of the Prostate (HoLEP) for benign prostatic hyperplasia (BPH). While some studies suggest that short-term use of these medications can reduce bleeding during surgery, there is …

40 - 80 years of age Male Phase N/A
Y Yulia Mulugeta

New Treatment Strategies and Epigenetic Biomarker for Management of Benign Prostatic Hyperplasia

SRD5A2 is a critical enzyme for prostatic development and growth, and the SRD5A2 inhibitor, finasteride, is used to treat benign prostatic hyperplasia (BPH). SRD5A2 is absent in 30% of normal adult men, which explains the resistance of a subset of patients to this commonly prescribed drug. This project proposes new …

18 years of age Male Phase 2
S Shachar Aharoni, Dr.

Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)

This study evaluates the long term safety and efficacy of use of the Butterfly Medical's prostatic retraction device in Benign Prostatic Hyperplasia (BPH) Patients. The study follows patients implanted with the Butterfly device for up to 5 year after implantation. The evaluations include recording of safety events and BPH related …

50 - 80 years of age Male Phase N/A
P Philippe ROUVELLAT, MD

Evaluation of Early Home Return in Patients With Enucleation of Prostate Adenoma

Prostate adenoma management includes, if necessary, surgical treatments: resection or vaporization by endoscopy or by open surgery in case of a very large prostate. Laser technology is a curative treatment for prostate adenoma. The minimum duration of hospitalization, in the context of enucleation prostatic endoscopy by laser, is estimated at …

45 years of age Male Phase N/A
S Sau Loi Ng, BN, DN

PUL vs TURP in BPH Patients With Urinary Retention

The study will be a prospective, randomized controlled trial comparing prostatic urethral lift (PUL) versus transurethral resection of prostate (TURP) in benign prostate hyperplasia (BPH) patients with urinary retention. The primary objective of this study is to compare the catheter-free rates of PUL vs TURP. Secondary objectives include comparison of …

40 years of age Male Phase N/A
E Emanuel Dias

Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients with BPH.

Benign prostatic hyperplasia (BPH) is one of the most prevalent human diseases and a major cause of lower urinary tract symptoms (LUTS). Some men respond to current medical treatment (mainly α-1 adrenoreceptor antagonists and 5 α-reductase inhibitors), but a large proportion of patients continues to need a surgical procedure to …

50 - 74 years of age Male Phase 2
I Iva Markovic

Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate

Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy. Holmium laser enucleation of the prostate (HoLEP) was the earliest form of prostate enucleation and is recommended by the …

18 years of age Male Phase N/A
A Alessia d'Arma, PhD

Protocollo N 2014 - Benign Prostatic Hyperplasia

Prospective observational study on the quality of life of patients with BPH under medical therapy and/or undergoing surgery.

18 years of age Male Phase N/A
C Chi Fai NG, MD

Perioperative Parameter and Treatment Outcomes of Surgical Treatment for Benign Prostate Hyperplasia in Hong Kong

This is a prospective data registry to assess the treatment outcomes and complications of different treatment approaches in our hospital clusters.

18 years of age Male Phase N/A
P Paolo Polverino

European Registry for Transperineal Laser Ablation of Prostate (TPLA) for Lower Urinary Tract Symptoms

The goal of this observational study is to assess mid- and long-term effectiveness of Transperineal Laser Ablation of Prostate (TPLA) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic obstruction measured by need and/or time until surgical retreatment. Data regarding patient-reported outcomes measures (PROMs), flowmetry parameters …

18 years of age Male Phase N/A

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