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solid-tumors Clinical Trials

A listing of solid-tumors medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,625 clinical trials

A Clinical Study of SPH7485 Tablets in the Treatment of Advanced Solid Tumors.

To evaluate the efficacy and safety of SPH7485 tablets in patients with advanced solid tumors.

18 - 75 years of age All Phase 1
X Xingchen Peng, Ph.D

a Polyphenol Whole Tumor Cell Vaccine in Patients With Advanced Malignant Solid Tumors

This project intends to carry out phase I clinical studies on the basis of the previous work, initially exploring the possible effective dose, evaluating its safety and tolerability, with a view to achieving long-term control of the disease, which is expected to provide more options for the treatment of patients …

18 - 65 years of age All Phase 1
B Beate Greer

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Hematopoietic stem cell transplantation can cure patients with blood cancer and other underlying diseases. αβ-T cell and B cell depletion has been introduced to decrease GVHD and PTLD and has demonstrated effectiveness for hematologic malignancies and non-malignant diseases additionally increasing the donor pool as to allow for haploidentical transplant to …

6 - 25 years of age All Phase 1/2
C Cai'e Wang, M.D.

A Phase I Study of SSGJ-612 in Patients With Advanced Solid Tumors

This study is an open-label phase I study to evaluate the safety, pharmacokinetics, and antitumor activity of SSGJ-612 in patients with advanced malignant solid tumors expressing HER2.

18 - 75 years of age All Phase 1
J Jinming Yu, PhD

Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

The main purpose of this study is to evaluate the safety and tolerability of IBI3005 and to determine the maximum tolerated dose (MTD) and the recommended Phase 2 Dose (RP2D) of IBI3005.

18 years of age All Phase 1

A Trial of HRS-6213 in Healthy Subjects and Patients With Solid Tumors

The study is being conducted to evaluate the safety, radiation dosimetry, pharmacokinetics, and preliminary diagnostic efficacy of HRS-6213.

18 - 75 years of age All Phase 1/2
Y Yuankai Shi, MD

A Phase 1 Study of CX1003 (Kanitinib) in Patients with Advanced Solid Tumors

CX1003 is a novel multi-target tyrosine kinase inhibitor that is designed to primarily inhibit vascular endothelial growth factor receptor 2 (VEGFR2) and hepatocyte growth factor receptor (HGFR/MET). This study aimed to evaluate the safety, pharmacokinetics, and antitumor activity of CX1003 in patients with refractory advanced or metastatic solid tumors.

18 years of age All Phase 1
A Agnes Harutyunyan

Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases

This early phase I trial evaluates different administration techniques (oral or intravenous) for arginine and tests the safety of giving arginine with whole brain radiation therapy in patients who have cancer that has spread from where it first started (primary site) to the brain (brain metastases). Arginine is an essential …

18 years of age All Phase 0
X Xiaorong Dong, PHD

Phase 1/2 Study of HS-10370 in Patients with Advanced Solid Tumors

HS-10370 is an oral, highly selective, small molecular inhibitor of KRAS G12C. This study will evaluate the safety, tolerability, pharmacokinetics and clinical activity of HS-10370 in Chinese advanced solid tumor patients.

18 years of age All Phase 1/2

Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies

Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of finding a drug that may be effective against tumors that have come back or that have not responded to standard therapy. The goals of this study are: To find …

1 - 30 years of age All Phase 1

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