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chemotherapy Clinical Trials

A listing of chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,571 clinical trials
Y Yu Wang, M.D.

Induction IBI110 and Sintilimab with Chemotherapy in LA HNSCC

This study aims to investigate the efficacy and safety of combining sintilimab and the TP regimen with/without IBI110 for neoadjuvant chemotherapy in resectable locally advanced head and neck squamous cell carcinoma (HNSCC).

18 - 75 years of age All Phase 1/2
j jin yang

Induction Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

This is a Phase II clinical study for patients with locally advanced cervical cancer, aimed at evaluating the efficacy, safety, and tolerability of Cadonilimab combined with chemotherapy as induction therapy.

18 years of age Female Phase 2
J Jin Jie

Blinatumomab Plus Reduced-dose Chemotherapy in Treating B-ALL

Precursor B cell acute lymphoblastic leukemia (B-ALL) is an aggressive type of leukemia, with high relapse rate and poor long term survival in adults. Traditional treatment regimens mainly include chemotherapy and hematopoietic stem cell transplantation. In the past decade, with the application of molecular targeted drugs and immunotherapy, the survival …

15 - 59 years of age All Phase 2
X Xin Sun

Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma

To evaluate the clinical application value in bone marrow protection of Trilaciclib in the neoadjuvant treatment of stage II/III classic osteosarcoma in combination with pirarubicin and lobaplatin.

14 - 70 years of age All Phase 2
F Fernanda Mesa-Chavez, MD, MSc

Online Mindfulness-based Stress Reduction for Patients Receiving Chemotherapy

The goal of this prospective, waitlist-controlled, 1:1 randomized study is to evaluate if an online mindfulness-based stress reduction (MBSR) intervention reduces treatment-related stress levels among patients with breast cancer receiving chemotherapy. The main questions it aims to answer are: Does an online MBSR intervention reduce stress levels (measured through the …

18 years of age Female Phase N/A
Z Zhongyu Yuan, Professor

Adaptive Chemotherapy for the Treatment of Advanced Breast Cancer

The primary objective of this study is to explore the efficacy and safety of adaptive therapy in the treatment of advanced breast cancer progressive after standard treatment.

18 - 75 years of age Female Phase 3
F Francesca Magnoni, MD

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC

This study will prospectively determine the feasibility and oncological safety of sentinel lymph node biopsy (SLNB) after neoadjuvant chemotherapy (NACT) in inflammatory breast cancer patients traditionally considered ineligible for SLNB due to locally advanced cancer with skin/chest wall involvement (cT4d) and heavy nodal burden at presentation (cN1/N2). This study will …

18 years of age Female Phase N/A
N Nader Sadeghi

Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.

The objective of this trial is to study the efficacy of treatment of human papilloma virus (HPV) related oropharyngeal cancer with chemotherapy followed by Transoral Robotic Surgery (TORS) as definitive treatment. Current treatment of oropharyngeal cancer are chemo-radiotherapy. There is significant lifelong side effects associated with this approach related to …

18 - 80 years of age All Phase 2
H Hong Yang, Ph.D.,M.D.

Neoadjuvant Osimertinib + Chemotherapy for EGFR-mutant Stage III NSCLC

This is a phase II, single-arm, multi-center study of neoadjuvant osimertinib in combination with chemotherapy for the treatment of patients with resectable EGFR-mutant stage III (N2) non-squamous non-small cell lung cancer

18 - 75 years of age All Phase 2

Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC

BR36 will evaluate the potential clinical benefit of tailoring immunotherapy treatment based on ctDNA molecular response in non-small cell lung cancer.

18 years of age All Phase 2/3

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