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neoplasms Clinical Trials

A listing of neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 14,282 clinical trials
T Thomas N Eade, MBBS

Lu-PSMA for Oligometastatic Prostate Cancer Treated With STereotactic Ablative Radiotherapy

The aim of this study is to assess the progression free survival (PFS) of SABR alone and SABR + 177Lu-prostate-specific membrane antigen (PSMA) in patients with oligometastatic prostate cancer undergoing PSMA positron emission tomography (PET) staging.

18 years of age Male Phase 2
O Oncology Clinical Research Referral Office

RAGE Inhibition to Decrease Cardiotoxicity in Women With Early Breast Cancer

This is a pilot study to evaluate the effects of azeliragon to decrease cardiac toxicity from chemotherapy and the safety of azelirgaon when given with chemotherapy. The Investigators hypothesize that there will be no significant interaction with Azeliragon and chemotherapy and that targeting the RAGE pathway will decrease anthracycline related …

18 years of age Female Phase 1/2

The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients

The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy. LACC patients undergoing radical synchronous chemoradiotherapy will be randomized into the experimental group receiving enteral immunonutrition therapy and the control group receiving standard enteral nutrition …

18 years of age Female Phase N/A
K Kaixuan Wang, MD

Establish Diagnostic Models Based on Portal Venous Blood for Pancreatic Cancer

Explore new markers based on portal venous blood sampling to establish novel diagnostic models for identification of malignant pancreatic mass.

18 - 80 years of age All Phase N/A
D Dominique GENRE, MD

Real Time Molecular Analysis of Breast Cancer Receiving Neo-adjuvant Chemotherapy

The present project aims at identifying robust candidates for drug resistance in BC patients eligible for NAC. Its originality lies upon the combination of three different and complementary prospective approaches: from the molecular analyses of biopsies sampled before and after NAC, from in vitro BC Patient-Derived Organoids (PDO) mimicking patient's …

18 years of age Female Phase N/A
A Adriana Espinosa, MD

Impact of ICCAN on Cancer Treatment Completion and Quality of Life

The purpose of this study is to see if the ICCAN program is working, and to compare the ICCAN program to the standard hospital services provided in New York City hospitals, like meeting with a Social Worker or a Patient Navigator (a person who provides personal hospital guidance).

21 - 80 years of age All Phase N/A
L Lorraine Portelance, MD

SMART TNT for the Conservative Management of Locally Advanced Rectal Cancer

The purpose of this research study is to find out how safe and effective is treating patients with locally advanced rectal cancer (LARC) with chemotherapy first and then follow with radiation therapy to a higher dose than what is usually delivered and see if patients could have complete response and …

18 years of age All Phase 1
R Research Nurse

Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor

The purpose of this study is to learn if certain drug combinations are effective treatments for patients with advanced ER+/HER2- who have previously been treated with palbociclib, ribociclib, or abemaciclib.

18 years of age Female Phase 2
S Shalaka Joshi, MS, MCh

A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer

To understand the effects induced by acute hypoxia that sets in during surgery in breast cancer. To study this, clinical samples (Tumor biopsies) will be obtained during the surgery after partial devascularisation (sample B) and stored for future genomic and proteonomic evaluations.

18 years of age Female Phase N/A
W Wenjin Yin

Capecitabine and Cyclophosphamide (XC) as Maintenance Therapy for Advanced Breast Cancer

To compare the efficacy and safety of capecitabine and cyclophosphamide (XC) versus physician's choice as maintenance therapy for patients with advanced breast cancer who achieved disease control after salvage treatment.

18 years of age Female Phase N/A

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