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cervical-dysplasia Clinical Trials

A listing of cervical-dysplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 70 clinical trials
Y Yebin Yu

Immune Persistence After the Whole Vaccination Shcedule With Recombination Quadrivalent HPV Vaccine

To access the immune persistence of Chinese women aged 9-45 years after receiving quadrivalent HPV vaccine with the immunization schedule of 0, 2 and 6 months.

9 - 45 years of age Female Phase N/A
K Karolina Louvanto, Prof

Sexual Function and Quality of Life After LEEP: a Prospective Multi-Center Study

The goal of this prospective study is to investigate the sexual function and quality of life of women undergoing loop electrosurgical excision procedure (LEEP) due to HPV-related cervical lesion. The main question it aims to answer are: Whether LEEP affects the sexual function of women in comparison to untreated women, …

18 - 70 years of age Female Phase N/A
G Giorgio Bogani

Adjuvant VaccInation After Conization for the Treatment for CervicAL Dysplasia

HPV vaccination has emerged as a strategy to reduce the risk of recurrence oafter excisional treatment. However, only few data are aviable. In this trial the investigators aim to assess the role of HPV vaccination in women traeted for HPV-related lesions

18 years of age Female Phase N/A
K Karla Alfaro, M.D.

Validation of a Lab-free Low-cost Screening Test for Prevention of Cervical Cancer

The purpose of this study is to validate Automated Visual Evaluation (AVE), specifically the CINFinder version developed by DL Analytics, a point-of-care screening and triage diagnostic tool for cervical cancer based on the assessment of digital images through artificial intelligence. Several teams around the world have developed versions of AVE …

30 - 59 years of age Female Phase N/A
T Ting Hu, MD,PhD

Clinical Evaluation of HPV Integration Triage for Detection of Cervical Precancer in HPV-positive Women

The American Society for Colposcopy and Cervical Pathology (ASCCP) recommended HPV testing or co-cytology testing as the standard primary approach for cervical cancer (CC) screening, which is highly sensitive for detection of cervical intraepithelial neoplasia grade 3 or worse. However, in clinical CC screening practice, the specificity and positive predictive …

20 - 70 years of age Female Phase N/A
T Tina Schmitz, BSN

Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical Cancer

The overarching objective of this project is to develop a pan-gynecologic cancer detection test using gynecologic (unique endometrial, cervical, and ovarian cancer) cancer-specific methylated DNA markers and high-risk human papilloma virus (HR-HPV) detected in vaginal fluid and/or plasma. This proposal defines Phase II MDM-based cancer detection studies in endometrial cancer …

18 years of age Female Phase N/A
M Merete Hædersdal, DMSc, MD

The Organ Transplant Recipient HPV and Skin Cancer Study

Solid organ transplant recipients (OTRs) receive lifelong immunosuppressive therapy, which puts them at increased risk of cutaneous and mucosal cancers. In particular, OTRs have increased risk of skin cancer and cancers caused by human papillomavirus (HPV), including cervical cancer and oropharyngeal cancer. There is currently limited knowledge on risk factors …

18 years of age All Phase N/A
C Cathy Visser, MSc

Screening Study for Cervical Pre-cancer and Cancer Prevention in South African Women.

Nearly 8 000 new cervical cancer cases are diagnosed in South Africa per year; many are still undiagnosed and about 50% of diagnosed cases succumb per year. Although the current prevalence of pre-cancer cervical disease is largely unknown, data from local studies suggest regional differences and an increase in the …

25 - 75 years of age Female Phase N/A
M Miriam Nakalembe

Prevention and Early Detection of Cervical Cancer Through Self-Administered Screening

This study examines prevention and early detection of cervical cancer through self-administration screening of patients in Western Uganda. The cervix is the opening of the uterus or womb, which is the organ that supports babies before they are born. There are simple tests that let doctors know whether or not …

25 - 49 years of age Female Phase N/A
L Lukas Dostalek

Regression of Cervical Precancerous Lesions and Associated Risk Factors

The aim of this study is to assess the extent of histopathological regression of severe cervical precancerous lesions (CIN 2 and CIN 3); evaluate the proportion of patients who experience the normalization of HPV test and cytology finding among those who were treated conservatively and those who underwent conization; and …

18 - 40 years of age Female Phase N/A

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